BDBM50177226 CHEMBL3813798

SMILES: COCCOc1nc(-c2ccc(C)cc2)n(n1)-c1ccc(NC(=O)CCl)cc1

InChI Key: InChIKey=JOADAKQTJNKLER-UHFFFAOYSA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50177226   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (Homo sapiens (Human))	BDBM50177226 (CHEMBL3813798) Show SMILES COCCOc1nc(-c2ccc(C)cc2)n(n1)-c1ccc(NC(=O)CCl)cc1 Show InChI InChI=1S/C20H21ClN4O3/c1-14-3-5-15(6-4-14)19-23-20(28-12-11-27-2)24-25(19)17-9-7-16(8-10-17)22-18(26)13-21/h3-10H,11-13H2,1-2H3,(H,22,26)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	9.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Leiden University Curated by ChEMBL					Assay Description Inhibition of recombinant Malt1 (unknown origin) at 10 to 1000 uM preincubated for 1 hr followed by (S)-1-((6-(4-(4-(5,5-Difluoro-3,7-bis(4-methoxyph...				Bioorg Med Chem 24: 3312-29 (2016) BindingDB Entry DOI: 10.7270/Q21G0P58
					More data for this Ligand-Target Pair
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (Homo sapiens (Human))	BDBM50177226 (CHEMBL3813798) Show SMILES COCCOc1nc(-c2ccc(C)cc2)n(n1)-c1ccc(NC(=O)CCl)cc1 Show InChI InChI=1S/C20H21ClN4O3/c1-14-3-5-15(6-4-14)19-23-20(28-12-11-27-2)24-25(19)17-9-7-16(8-10-17)22-18(26)13-21/h3-10H,11-13H2,1-2H3,(H,22,26)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	8.13E+3	n/a	n/a	n/a	n/a	n/a	n/a
Leiden University Curated by ChEMBL					Assay Description Inhibition of recombinant Malt1 (unknown origin) at 1 to 100 uM preincubated for 1 hr followed by (S)-1-((6-(4-(4-(5,5-Difluoro-3,7-bis(4-methoxyphen...				Bioorg Med Chem 24: 3312-29 (2016) BindingDB Entry DOI: 10.7270/Q21G0P58
					More data for this Ligand-Target Pair
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (Homo sapiens (Human))	BDBM50177226 (CHEMBL3813798) Show SMILES COCCOc1nc(-c2ccc(C)cc2)n(n1)-c1ccc(NC(=O)CCl)cc1 Show InChI InChI=1S/C20H21ClN4O3/c1-14-3-5-15(6-4-14)19-23-20(28-12-11-27-2)24-25(19)17-9-7-16(8-10-17)22-18(26)13-21/h3-10H,11-13H2,1-2H3,(H,22,26)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	8.91E+3	n/a	n/a	n/a	n/a	n/a	n/a
Leiden University Curated by ChEMBL					Assay Description Inhibition of recombinant Malt1 (unknown origin) at 10 to 1000 uM preincubated for 1 hr followed by (S)-1-((6-(4-(4-(5,5-Difluoro-3,7-bis(4-methoxyph...				Bioorg Med Chem 24: 3312-29 (2016) BindingDB Entry DOI: 10.7270/Q21G0P58
					More data for this Ligand-Target Pair
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (Homo sapiens (Human))	BDBM50177226 (CHEMBL3813798) Show SMILES COCCOc1nc(-c2ccc(C)cc2)n(n1)-c1ccc(NC(=O)CCl)cc1 Show InChI InChI=1S/C20H21ClN4O3/c1-14-3-5-15(6-4-14)19-23-20(28-12-11-27-2)24-25(19)17-9-7-16(8-10-17)22-18(26)13-21/h3-10H,11-13H2,1-2H3,(H,22,26)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	8.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Leiden University Curated by ChEMBL					Assay Description Inhibition of recombinant Malt1 (unknown origin) at 1 to 100 uM preincubated for 1 hr followed by (S)-1-((6-(4-(4-(5,5-Difluoro-3,7-bis(4-methoxyphen...				Bioorg Med Chem 24: 3312-29 (2016) BindingDB Entry DOI: 10.7270/Q21G0P58
					More data for this Ligand-Target Pair