BDBM50177466 CHEMBL203765::N-benzyl-N-methyl-1-(3-((4-oxo-3,4-dihydrophthalazin-1-yl)methyl)benzoyl)piperidine-4-carboxamide

SMILES: CN(Cc1ccccc1)C(=O)C1CCN(CC1)C(=O)c1cccc(Cc2n[nH]c(=O)c3ccccc23)c1

InChI Key: InChIKey=UIZWWEQUPPQYDE-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50177466   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Poly [ADP-ribose] polymerase 1 (Homo sapiens (Human))	BDBM50177466 (CHEMBL203765 | N-benzyl-N-methyl-1-(3-((4-oxo-3,4-...) Show SMILES CN(Cc1ccccc1)C(=O)C1CCN(CC1)C(=O)c1cccc(Cc2n[nH]c(=O)c3ccccc23)c1 Show InChI InChI=1S/C30H30N4O3/c1-33(20-21-8-3-2-4-9-21)29(36)23-14-16-34(17-15-23)30(37)24-11-7-10-22(18-24)19-27-25-12-5-6-13-26(25)28(35)32-31-27/h2-13,18,23H,14-17,19-20H2,1H3,(H,32,35)	PDB MMDB UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
KuDOS Pharmaceuticals Ltd Curated by ChEMBL					Assay Description Inhibitory activity against PARP1				Bioorg Med Chem Lett 16: 1040-4 (2006) Article DOI: 10.1016/j.bmcl.2005.10.081 BindingDB Entry DOI: 10.7270/Q25T3K12
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