BDBM50177923 2-cyano-N-{3-[2-cyano-3-(3,4,5-trihydroxyphenyl)acryloylamino]pentyl}-3-(3,4,5-trihydroxyphenyl)acrylamide::CHEMBL196854

SMILES: Oc1cc(\C=C(/C#N)C(=O)NCCCCCNC(=O)C(=C\c2cc(O)c(O)c(O)c2)\C#N)cc(O)c1O

InChI Key: InChIKey=JQUXJGYSUIMLTN-KGMKFKQSSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50177923   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dynamin-1 (Homo sapiens (Human))	BDBM50177923 (2-cyano-N-{3-[2-cyano-3-(3,4,5-trihydroxyphenyl)ac...) Show SMILES Oc1cc(\C=C(/C#N)C(=O)NCCCCCNC(=O)C(=C\c2cc(O)c(O)c(O)c2)\C#N)cc(O)c1O Show InChI InChI=1S/C25H24N4O8/c26-12-16(6-14-8-18(30)22(34)19(31)9-14)24(36)28-4-2-1-3-5-29-25(37)17(13-27)7-15-10-20(32)23(35)21(33)11-15/h6-11,30-35H,1-5H2,(H,28,36)(H,29,37)/b16-6+,17-7+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
The University of Newcastle Curated by ChEMBL					Assay Description Inhibitory activity against dynamin1 GTPase expressed in sheep brain				J Med Chem 48: 7781-8 (2005) Article DOI: 10.1021/jm040208l BindingDB Entry DOI: 10.7270/Q2BC3Z41
					More data for this Ligand-Target Pair