BDBM50179223 4-chloro-N-(6,7-dimethoxy-2,4-dihydroindeno[1,2-c]pyrazol-3-yl)phenylamine::CHEMBL425751

SMILES: COc1cc2Cc3c(Nc4ccc(Cl)cc4)[nH]nc3-c2cc1OC

InChI Key: InChIKey=XRRBNRLNVPJQKM-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50179223   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM50179223 (4-chloro-N-(6,7-dimethoxy-2,4-dihydroindeno[1,2-c]...) Show SMILES COc1cc2Cc3c(Nc4ccc(Cl)cc4)[nH]nc3-c2cc1OC Show InChI InChI=1S/C18H16ClN3O2/c1-23-15-8-10-7-14-17(13(10)9-16(15)24-2)21-22-18(14)20-12-5-3-11(19)4-6-12/h3-6,8-9H,7H2,1-2H3,(H2,20,21,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	659	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Inhibitory activity against PDGFRbeta kinase				J Med Chem 48: 8163-73 (2005) Article DOI: 10.1021/jm050680m BindingDB Entry DOI: 10.7270/Q2W095HW
					More data for this Ligand-Target Pair