BDBM50179473 2-((2-(6-(4-tert-butylphenyl)pyridin-2-yl)-1H-benzo[d]imidazol-5-yl)methyl)malonic acid::CHEMBL202796

SMILES: CC(C)(C)c1ccc(cc1)-c1cccc(n1)-c1nc2ccc(CC(C(O)=O)C(O)=O)cc2[nH]1

InChI Key: InChIKey=IZLPISHIQSVOSP-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50179473   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Thrombopoietin receptor (Homo sapiens (Human))	BDBM50179473 (2-((2-(6-(4-tert-butylphenyl)pyridin-2-yl)-1H-benz...) Show SMILES CC(C)(C)c1ccc(cc1)-c1cccc(n1)-c1nc2ccc(CC(C(O)=O)C(O)=O)cc2[nH]1 Show InChI InChI=1S/C26H25N3O4/c1-26(2,3)17-10-8-16(9-11-17)19-5-4-6-21(27-19)23-28-20-12-7-15(14-22(20)29-23)13-18(24(30)31)25(32)33/h4-12,14,18H,13H2,1-3H3,(H,28,29)(H,30,31)(H,32,33)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a
GlaxoSmithKline Pharmaceuticals Curated by ChEMBL					Assay Description Agonist activity as induced proliferation in Ba/F3-hTpoR murine lymphocyte expressing human TPOR				Bioorg Med Chem Lett 16: 1212-6 (2006) Article DOI: 10.1016/j.bmcl.2005.11.096 BindingDB Entry DOI: 10.7270/Q2V124BM
					More data for this Ligand-Target Pair