BDBM50179642 1-(3-chlorophenyl)-3-(1-ethyl-5-methyl-4-oxoimidazolidin-2-ylidene)urea::CHEMBL202845

SMILES: CCn1c(C)c(O)nc1NC(=O)Nc1cccc(Cl)c1

InChI Key: InChIKey=YUEORBSSOODDSG-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50179642   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50179642 (1-(3-chlorophenyl)-3-(1-ethyl-5-methyl-4-oxoimidaz...) Show SMILES CCn1c(C)c(O)nc1NC(=O)Nc1cccc(Cl)c1 Show InChI InChI=1S/C13H15ClN4O2/c1-3-18-8(2)11(19)16-12(18)17-13(20)15-10-6-4-5-9(14)7-10/h4-7,19H,3H2,1-2H3,(H2,15,16,17,20)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	410	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D Curated by ChEMBL					Assay Description Inhibition of glutamate-induced calcium influx in human mGluR5d by FLIPR				Bioorg Med Chem Lett 16: 1142-5 (2006) Article DOI: 10.1016/j.bmcl.2005.11.092 BindingDB Entry DOI: 10.7270/Q2697348
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor (Rattus norvegicus (Rat))	BDBM50179642 (1-(3-chlorophenyl)-3-(1-ethyl-5-methyl-4-oxoimidaz...) Show SMILES CCn1c(C)c(O)nc1NC(=O)Nc1cccc(Cl)c1 Show InChI InChI=1S/C13H15ClN4O2/c1-3-18-8(2)11(19)16-12(18)17-13(20)15-10-6-4-5-9(14)7-10/h4-7,19H,3H2,1-2H3,(H2,15,16,17,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	320	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R&D Curated by ChEMBL					Assay Description Displacement of [3H]MPEP from mGluR5d in rat brain membrane				Bioorg Med Chem Lett 16: 1142-5 (2006) Article DOI: 10.1016/j.bmcl.2005.11.092 BindingDB Entry DOI: 10.7270/Q2697348
					More data for this Ligand-Target Pair