BDBM50179930 2'-Fluoro-5'-[7-(1-hydroxy-1-methyl-ethyl)-imidazo[1,2-a]pyridin-3-yl]-biphenyl-2-carbonitrile::CHEMBL206196

SMILES: CC(C)(O)c1ccn2c(cnc2c1)-c1ccc(F)c(c1)-c1ccccc1C#N

InChI Key: InChIKey=SOLFHEZOCDBPSQ-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50179930   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
GABA receptor alpha-1/beta-3/gamma-2 subunit (Homo sapiens (Human))	BDBM50179930 (2'-Fluoro-5'-[7-(1-hydroxy-1-methyl-ethyl)-imidazo...) Show SMILES CC(C)(O)c1ccn2c(cnc2c1)-c1ccc(F)c(c1)-c1ccccc1C#N Show InChI InChI=1S/C23H18FN3O/c1-23(2,28)17-9-10-27-21(14-26-22(27)12-17)15-7-8-20(24)19(11-15)18-6-4-3-5-16(18)13-25/h3-12,14,28H,1-2H3	PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.35	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp and Dohme Curated by ChEMBL					Assay Description Displacement of [3H]Ro 15-1788 from human GABA-Aalpha1 receptor plus beta3gamma2 expressed in mouse L(tk-) cells				Bioorg Med Chem Lett 16: 1518-22 (2006) Article DOI: 10.1016/j.bmcl.2005.12.037 BindingDB Entry DOI: 10.7270/Q2HM582K
					More data for this Ligand-Target Pair
GABA receptor alpha-3/beta-3/gamma-2 subunit (Homo sapiens (Human))	BDBM50179930 (2'-Fluoro-5'-[7-(1-hydroxy-1-methyl-ethyl)-imidazo...) Show SMILES CC(C)(O)c1ccn2c(cnc2c1)-c1ccc(F)c(c1)-c1ccccc1C#N Show InChI InChI=1S/C23H18FN3O/c1-23(2,28)17-9-10-27-21(14-26-22(27)12-17)15-7-8-20(24)19(11-15)18-6-4-3-5-16(18)13-25/h3-12,14,28H,1-2H3	PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5.16	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp and Dohme Curated by ChEMBL					Assay Description Displacement of [3H]Ro 15-1788 from human GABA-Aalpha3 receptor plus beta3gamma2 expressed in mouse L(tk-) cells				Bioorg Med Chem Lett 16: 1518-22 (2006) Article DOI: 10.1016/j.bmcl.2005.12.037 BindingDB Entry DOI: 10.7270/Q2HM582K
					More data for this Ligand-Target Pair