BDBM50179962 1-(3-methanesulfonyl-6,11-dihydro-5-thia-12-aza-dibenzo[a,e]cycloocten-12-yl)-ethanone::CHEMBL205769
SMILES: CC(=O)N1Cc2ccccc2CSc2cc(ccc12)S(C)(=O)=O
InChI Key: InChIKey=DFFMWVCVVVAYIA-UHFFFAOYSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
17-beta-hydroxysteroid dehydrogenase type 3 (Homo sapiens (Human)) | BDBM50179962 (1-(3-methanesulfonyl-6,11-dihydro-5-thia-12-aza-di...) | Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL | Assay Description Inhibition of 17beta-HSD3 | Bioorg Med Chem Lett 16: 1532-6 (2006) Article DOI: 10.1016/j.bmcl.2005.12.039 BindingDB Entry DOI: 10.7270/Q2CV4HBV | |||||||||||
More data for this Ligand-Target Pair |