BDBM50180080 3-[2-[5-chloro-1-(diphenylmethyl)-2-methyl-1H-indol-3-yl]-ethoxy]isoxazole-5-carboxylic acid::CHEMBL381114

SMILES: Cc1c(CCOc2cc(on2)C(O)=O)c2cc(Cl)ccc2n1C(c1ccccc1)c1ccccc1

InChI Key: InChIKey=RHQROKKYSBRSGA-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50180080   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cPLA2 C2 (Homo sapiens (Human))	BDBM50180080 (3-[2-[5-chloro-1-(diphenylmethyl)-2-methyl-1H-indo...) Show SMILES Cc1c(CCOc2cc(on2)C(O)=O)c2cc(Cl)ccc2n1C(c1ccccc1)c1ccccc1 Show InChI InChI=1S/C28H23ClN2O4/c1-18-22(14-15-34-26-17-25(28(32)33)35-30-26)23-16-21(29)12-13-24(23)31(18)27(19-8-4-2-5-9-19)20-10-6-3-7-11-20/h2-13,16-17,27H,14-15H2,1H3,(H,32,33)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of cytosolic phospholipase A2-alpha in GLU micelle assay				J Med Chem 49: 135-58 (2006) Article DOI: 10.1021/jm0507882 BindingDB Entry DOI: 10.7270/Q2MC8ZMP
					More data for this Ligand-Target Pair