null

SMILES: COc1c(C)cc(cc1C)-c1[nH]c2ccc(cc2c1[C@H](C)CNCCc1ccccc1)C(C)(C)C(=O)N(CC(C)C)CC(C)C

InChI Key: InChIKey=CXPNKNXEHYPKJI-SSEXGKCCSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 71 hits for monomerid = 50180787   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50180787 ((S)-N,N-diisobutyl-2-(2-(4-methoxy-3,5-dimethylphe...) Show SMILES COc1c(C)cc(cc1C)-c1[nH]c2ccc(cc2c1[C@H](C)CNCCc1ccccc1)C(C)(C)C(=O)N(CC(C)C)CC(C)C Show InChI InChI=1S/C40H55N3O2/c1-26(2)24-43(25-27(3)4)39(44)40(8,9)33-16-17-35-34(22-33)36(30(7)23-41-19-18-31-14-12-11-13-15-31)37(42-35)32-20-28(5)38(45-10)29(6)21-32/h11-17,20-22,26-27,30,41-42H,18-19,23-25H2,1-10H3/t30-/m1/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.70	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR N305K				J Med Chem 49: 637-47 (2006) Article DOI: 10.1021/jm0506928 BindingDB Entry DOI: 10.7270/Q24749GS
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50180787 ((S)-N,N-diisobutyl-2-(2-(4-methoxy-3,5-dimethylphe...) Show SMILES COc1c(C)cc(cc1C)-c1[nH]c2ccc(cc2c1[C@H](C)CNCCc1ccccc1)C(C)(C)C(=O)N(CC(C)C)CC(C)C Show InChI InChI=1S/C40H55N3O2/c1-26(2)24-43(25-27(3)4)39(44)40(8,9)33-16-17-35-34(22-33)36(30(7)23-41-19-18-31-14-12-11-13-15-31)37(42-35)32-20-28(5)38(45-10)29(6)21-32/h11-17,20-22,26-27,30,41-42H,18-19,23-25H2,1-10H3/t30-/m1/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	16.9	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR F272L				J Med Chem 49: 637-47 (2006) Article DOI: 10.1021/jm0506928 BindingDB Entry DOI: 10.7270/Q24749GS
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50180787 ((S)-N,N-diisobutyl-2-(2-(4-methoxy-3,5-dimethylphe...) Show SMILES COc1c(C)cc(cc1C)-c1[nH]c2ccc(cc2c1[C@H](C)CNCCc1ccccc1)C(C)(C)C(=O)N(CC(C)C)CC(C)C Show InChI InChI=1S/C40H55N3O2/c1-26(2)24-43(25-27(3)4)39(44)40(8,9)33-16-17-35-34(22-33)36(30(7)23-41-19-18-31-14-12-11-13-15-31)37(42-35)32-20-28(5)38(45-10)29(6)21-32/h11-17,20-22,26-27,30,41-42H,18-19,23-25H2,1-10H3/t30-/m1/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	41.4	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR S203P				J Med Chem 49: 637-47 (2006) Article DOI: 10.1021/jm0506928 BindingDB Entry DOI: 10.7270/Q24749GS
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50180787 ((S)-N,N-diisobutyl-2-(2-(4-methoxy-3,5-dimethylphe...) Show SMILES COc1c(C)cc(cc1C)-c1[nH]c2ccc(cc2c1[C@H](C)CNCCc1ccccc1)C(C)(C)C(=O)N(CC(C)C)CC(C)C Show InChI InChI=1S/C40H55N3O2/c1-26(2)24-43(25-27(3)4)39(44)40(8,9)33-16-17-35-34(22-33)36(30(7)23-41-19-18-31-14-12-11-13-15-31)37(42-35)32-20-28(5)38(45-10)29(6)21-32/h11-17,20-22,26-27,30,41-42H,18-19,23-25H2,1-10H3/t30-/m1/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	47.1	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR N315A				J Med Chem 49: 637-47 (2006) Article DOI: 10.1021/jm0506928 BindingDB Entry DOI: 10.7270/Q24749GS
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50180787 ((S)-N,N-diisobutyl-2-(2-(4-methoxy-3,5-dimethylphe...) Show SMILES COc1c(C)cc(cc1C)-c1[nH]c2ccc(cc2c1[C@H](C)CNCCc1ccccc1)C(C)(C)C(=O)N(CC(C)C)CC(C)C Show InChI InChI=1S/C40H55N3O2/c1-26(2)24-43(25-27(3)4)39(44)40(8,9)33-16-17-35-34(22-33)36(30(7)23-41-19-18-31-14-12-11-13-15-31)37(42-35)32-20-28(5)38(45-10)29(6)21-32/h11-17,20-22,26-27,30,41-42H,18-19,23-25H2,1-10H3/t30-/m1/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	49.3	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR N315D				J Med Chem 49: 637-47 (2006) Article DOI: 10.1021/jm0506928 BindingDB Entry DOI: 10.7270/Q24749GS
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50180787 ((S)-N,N-diisobutyl-2-(2-(4-methoxy-3,5-dimethylphe...) Show SMILES COc1c(C)cc(cc1C)-c1[nH]c2ccc(cc2c1[C@H](C)CNCCc1ccccc1)C(C)(C)C(=O)N(CC(C)C)CC(C)C Show InChI InChI=1S/C40H55N3O2/c1-26(2)24-43(25-27(3)4)39(44)40(8,9)33-16-17-35-34(22-33)36(30(7)23-41-19-18-31-14-12-11-13-15-31)37(42-35)32-20-28(5)38(45-10)29(6)21-32/h11-17,20-22,26-27,30,41-42H,18-19,23-25H2,1-10H3/t30-/m1/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	60.1	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR F309L				J Med Chem 49: 637-47 (2006) Article DOI: 10.1021/jm0506928 BindingDB Entry DOI: 10.7270/Q24749GS
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50180787 ((S)-N,N-diisobutyl-2-(2-(4-methoxy-3,5-dimethylphe...) Show SMILES COc1c(C)cc(cc1C)-c1[nH]c2ccc(cc2c1[C@H](C)CNCCc1ccccc1)C(C)(C)C(=O)N(CC(C)C)CC(C)C Show InChI InChI=1S/C40H55N3O2/c1-26(2)24-43(25-27(3)4)39(44)40(8,9)33-16-17-35-34(22-33)36(30(7)23-41-19-18-31-14-12-11-13-15-31)37(42-35)32-20-28(5)38(45-10)29(6)21-32/h11-17,20-22,26-27,30,41-42H,18-19,23-25H2,1-10H3/t30-/m1/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR Q189A				J Med Chem 49: 637-47 (2006) Article DOI: 10.1021/jm0506928 BindingDB Entry DOI: 10.7270/Q24749GS
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50180787 ((S)-N,N-diisobutyl-2-(2-(4-methoxy-3,5-dimethylphe...) Show SMILES COc1c(C)cc(cc1C)-c1[nH]c2ccc(cc2c1[C@H](C)CNCCc1ccccc1)C(C)(C)C(=O)N(CC(C)C)CC(C)C Show InChI InChI=1S/C40H55N3O2/c1-26(2)24-43(25-27(3)4)39(44)40(8,9)33-16-17-35-34(22-33)36(30(7)23-41-19-18-31-14-12-11-13-15-31)37(42-35)32-20-28(5)38(45-10)29(6)21-32/h11-17,20-22,26-27,30,41-42H,18-19,23-25H2,1-10H3/t30-/m1/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	101	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR H306K				J Med Chem 49: 637-47 (2006) Article DOI: 10.1021/jm0506928 BindingDB Entry DOI: 10.7270/Q24749GS
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50180787 ((S)-N,N-diisobutyl-2-(2-(4-methoxy-3,5-dimethylphe...) Show SMILES COc1c(C)cc(cc1C)-c1[nH]c2ccc(cc2c1[C@H](C)CNCCc1ccccc1)C(C)(C)C(=O)N(CC(C)C)CC(C)C Show InChI InChI=1S/C40H55N3O2/c1-26(2)24-43(25-27(3)4)39(44)40(8,9)33-16-17-35-34(22-33)36(30(7)23-41-19-18-31-14-12-11-13-15-31)37(42-35)32-20-28(5)38(45-10)29(6)21-32/h11-17,20-22,26-27,30,41-42H,18-19,23-25H2,1-10H3/t30-/m1/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	15.2	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR E295Q				J Med Chem 49: 637-47 (2006) Article DOI: 10.1021/jm0506928 BindingDB Entry DOI: 10.7270/Q24749GS
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50180787 ((S)-N,N-diisobutyl-2-(2-(4-methoxy-3,5-dimethylphe...) Show SMILES COc1c(C)cc(cc1C)-c1[nH]c2ccc(cc2c1[C@H](C)CNCCc1ccccc1)C(C)(C)C(=O)N(CC(C)C)CC(C)C Show InChI InChI=1S/C40H55N3O2/c1-26(2)24-43(25-27(3)4)39(44)40(8,9)33-16-17-35-34(22-33)36(30(7)23-41-19-18-31-14-12-11-13-15-31)37(42-35)32-20-28(5)38(45-10)29(6)21-32/h11-17,20-22,26-27,30,41-42H,18-19,23-25H2,1-10H3/t30-/m1/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	20.6	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR D302Q				J Med Chem 49: 637-47 (2006) Article DOI: 10.1021/jm0506928 BindingDB Entry DOI: 10.7270/Q24749GS
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50180787 ((S)-N,N-diisobutyl-2-(2-(4-methoxy-3,5-dimethylphe...) Show SMILES COc1c(C)cc(cc1C)-c1[nH]c2ccc(cc2c1[C@H](C)CNCCc1ccccc1)C(C)(C)C(=O)N(CC(C)C)CC(C)C Show InChI InChI=1S/C40H55N3O2/c1-26(2)24-43(25-27(3)4)39(44)40(8,9)33-16-17-35-34(22-33)36(30(7)23-41-19-18-31-14-12-11-13-15-31)37(42-35)32-20-28(5)38(45-10)29(6)21-32/h11-17,20-22,26-27,30,41-42H,18-19,23-25H2,1-10H3/t30-/m1/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	17.9	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR M24A				J Med Chem 49: 637-47 (2006) Article DOI: 10.1021/jm0506928 BindingDB Entry DOI: 10.7270/Q24749GS
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50180787 ((S)-N,N-diisobutyl-2-(2-(4-methoxy-3,5-dimethylphe...) Show SMILES COc1c(C)cc(cc1C)-c1[nH]c2ccc(cc2c1[C@H](C)CNCCc1ccccc1)C(C)(C)C(=O)N(CC(C)C)CC(C)C Show InChI InChI=1S/C40H55N3O2/c1-26(2)24-43(25-27(3)4)39(44)40(8,9)33-16-17-35-34(22-33)36(30(7)23-41-19-18-31-14-12-11-13-15-31)37(42-35)32-20-28(5)38(45-10)29(6)21-32/h11-17,20-22,26-27,30,41-42H,18-19,23-25H2,1-10H3/t30-/m1/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	10.8	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR N27E				J Med Chem 49: 637-47 (2006) Article DOI: 10.1021/jm0506928 BindingDB Entry DOI: 10.7270/Q24749GS
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50180787 ((S)-N,N-diisobutyl-2-(2-(4-methoxy-3,5-dimethylphe...) Show SMILES COc1c(C)cc(cc1C)-c1[nH]c2ccc(cc2c1[C@H](C)CNCCc1ccccc1)C(C)(C)C(=O)N(CC(C)C)CC(C)C Show InChI InChI=1S/C40H55N3O2/c1-26(2)24-43(25-27(3)4)39(44)40(8,9)33-16-17-35-34(22-33)36(30(7)23-41-19-18-31-14-12-11-13-15-31)37(42-35)32-20-28(5)38(45-10)29(6)21-32/h11-17,20-22,26-27,30,41-42H,18-19,23-25H2,1-10H3/t30-/m1/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	56.1	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR D293K				J Med Chem 49: 637-47 (2006) Article DOI: 10.1021/jm0506928 BindingDB Entry DOI: 10.7270/Q24749GS
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50180787 ((S)-N,N-diisobutyl-2-(2-(4-methoxy-3,5-dimethylphe...) Show SMILES COc1c(C)cc(cc1C)-c1[nH]c2ccc(cc2c1[C@H](C)CNCCc1ccccc1)C(C)(C)C(=O)N(CC(C)C)CC(C)C Show InChI InChI=1S/C40H55N3O2/c1-26(2)24-43(25-27(3)4)39(44)40(8,9)33-16-17-35-34(22-33)36(30(7)23-41-19-18-31-14-12-11-13-15-31)37(42-35)32-20-28(5)38(45-10)29(6)21-32/h11-17,20-22,26-27,30,41-42H,18-19,23-25H2,1-10H3/t30-/m1/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	229	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR Y290Q				J Med Chem 49: 637-47 (2006) Article DOI: 10.1021/jm0506928 BindingDB Entry DOI: 10.7270/Q24749GS
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50180787 ((S)-N,N-diisobutyl-2-(2-(4-methoxy-3,5-dimethylphe...) Show SMILES COc1c(C)cc(cc1C)-c1[nH]c2ccc(cc2c1[C@H](C)CNCCc1ccccc1)C(C)(C)C(=O)N(CC(C)C)CC(C)C Show InChI InChI=1S/C40H55N3O2/c1-26(2)24-43(25-27(3)4)39(44)40(8,9)33-16-17-35-34(22-33)36(30(7)23-41-19-18-31-14-12-11-13-15-31)37(42-35)32-20-28(5)38(45-10)29(6)21-32/h11-17,20-22,26-27,30,41-42H,18-19,23-25H2,1-10H3/t30-/m1/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	82.3	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR K121A				J Med Chem 49: 637-47 (2006) Article DOI: 10.1021/jm0506928 BindingDB Entry DOI: 10.7270/Q24749GS
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50180787 ((S)-N,N-diisobutyl-2-(2-(4-methoxy-3,5-dimethylphe...) Show SMILES COc1c(C)cc(cc1C)-c1[nH]c2ccc(cc2c1[C@H](C)CNCCc1ccccc1)C(C)(C)C(=O)N(CC(C)C)CC(C)C Show InChI InChI=1S/C40H55N3O2/c1-26(2)24-43(25-27(3)4)39(44)40(8,9)33-16-17-35-34(22-33)36(30(7)23-41-19-18-31-14-12-11-13-15-31)37(42-35)32-20-28(5)38(45-10)29(6)21-32/h11-17,20-22,26-27,30,41-42H,18-19,23-25H2,1-10H3/t30-/m1/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	15.8	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR Q189K				J Med Chem 49: 637-47 (2006) Article DOI: 10.1021/jm0506928 BindingDB Entry DOI: 10.7270/Q24749GS
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50180787 ((S)-N,N-diisobutyl-2-(2-(4-methoxy-3,5-dimethylphe...) Show SMILES COc1c(C)cc(cc1C)-c1[nH]c2ccc(cc2c1[C@H](C)CNCCc1ccccc1)C(C)(C)C(=O)N(CC(C)C)CC(C)C Show InChI InChI=1S/C40H55N3O2/c1-26(2)24-43(25-27(3)4)39(44)40(8,9)33-16-17-35-34(22-33)36(30(7)23-41-19-18-31-14-12-11-13-15-31)37(42-35)32-20-28(5)38(45-10)29(6)21-32/h11-17,20-22,26-27,30,41-42H,18-19,23-25H2,1-10H3/t30-/m1/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR K191E				J Med Chem 49: 637-47 (2006) Article DOI: 10.1021/jm0506928 BindingDB Entry DOI: 10.7270/Q24749GS
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50180787 ((S)-N,N-diisobutyl-2-(2-(4-methoxy-3,5-dimethylphe...) Show SMILES COc1c(C)cc(cc1C)-c1[nH]c2ccc(cc2c1[C@H](C)CNCCc1ccccc1)C(C)(C)C(=O)N(CC(C)C)CC(C)C Show InChI InChI=1S/C40H55N3O2/c1-26(2)24-43(25-27(3)4)39(44)40(8,9)33-16-17-35-34(22-33)36(30(7)23-41-19-18-31-14-12-11-13-15-31)37(42-35)32-20-28(5)38(45-10)29(6)21-32/h11-17,20-22,26-27,30,41-42H,18-19,23-25H2,1-10H3/t30-/m1/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	22.4	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR L112A				J Med Chem 49: 637-47 (2006) Article DOI: 10.1021/jm0506928 BindingDB Entry DOI: 10.7270/Q24749GS
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50180787 ((S)-N,N-diisobutyl-2-(2-(4-methoxy-3,5-dimethylphe...) Show SMILES COc1c(C)cc(cc1C)-c1[nH]c2ccc(cc2c1[C@H](C)CNCCc1ccccc1)C(C)(C)C(=O)N(CC(C)C)CC(C)C Show InChI InChI=1S/C40H55N3O2/c1-26(2)24-43(25-27(3)4)39(44)40(8,9)33-16-17-35-34(22-33)36(30(7)23-41-19-18-31-14-12-11-13-15-31)37(42-35)32-20-28(5)38(45-10)29(6)21-32/h11-17,20-22,26-27,30,41-42H,18-19,23-25H2,1-10H3/t30-/m1/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	63.7	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR S118N				J Med Chem 49: 637-47 (2006) Article DOI: 10.1021/jm0506928 BindingDB Entry DOI: 10.7270/Q24749GS
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50180787 ((S)-N,N-diisobutyl-2-(2-(4-methoxy-3,5-dimethylphe...) Show SMILES COc1c(C)cc(cc1C)-c1[nH]c2ccc(cc2c1[C@H](C)CNCCc1ccccc1)C(C)(C)C(=O)N(CC(C)C)CC(C)C Show InChI InChI=1S/C40H55N3O2/c1-26(2)24-43(25-27(3)4)39(44)40(8,9)33-16-17-35-34(22-33)36(30(7)23-41-19-18-31-14-12-11-13-15-31)37(42-35)32-20-28(5)38(45-10)29(6)21-32/h11-17,20-22,26-27,30,41-42H,18-19,23-25H2,1-10H3/t30-/m1/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.90	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR S168A				J Med Chem 49: 637-47 (2006) Article DOI: 10.1021/jm0506928 BindingDB Entry DOI: 10.7270/Q24749GS
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50180787 ((S)-N,N-diisobutyl-2-(2-(4-methoxy-3,5-dimethylphe...) Show SMILES COc1c(C)cc(cc1C)-c1[nH]c2ccc(cc2c1[C@H](C)CNCCc1ccccc1)C(C)(C)C(=O)N(CC(C)C)CC(C)C Show InChI InChI=1S/C40H55N3O2/c1-26(2)24-43(25-27(3)4)39(44)40(8,9)33-16-17-35-34(22-33)36(30(7)23-41-19-18-31-14-12-11-13-15-31)37(42-35)32-20-28(5)38(45-10)29(6)21-32/h11-17,20-22,26-27,30,41-42H,18-19,23-25H2,1-10H3/t30-/m1/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	14.6	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Displacement of [125I-His5, D-Tyr6]GnRH from mutant GnRHR, GnRHR S203K				J Med Chem 49: 637-47 (2006) Article DOI: 10.1021/jm0506928 BindingDB Entry DOI: 10.7270/Q24749GS
					More data for this Ligand-Target Pair