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SMILES: Cn1ncc2c(N)c(-c3nc4ccccc4[nH]3)c(=O)[nH]c12

InChI Key: InChIKey=QMMKNQNBDPGVTP-UHFFFAOYSA-N

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50181316   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Vascular endothelial growth factor receptor 1


(Homo sapiens (Human))
BDBM50181316
PNG
(4-amino-5-(1H-benzo[d]imidazol-2-yl)-1-methyl-1H-p...)
Show SMILES Cn1ncc2c(N)c(-c3nc4ccccc4[nH]3)c(=O)[nH]c12
Show InChI InChI=1S/C14H12N6O/c1-20-13-7(6-16-20)11(15)10(14(21)19-13)12-17-8-4-2-3-5-9(8)18-12/h2-6H,1H3,(H,17,18)(H3,15,19,21)
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Article
PubMed
n/an/a 4.30E+3n/an/an/an/an/an/a



Chiron Corporation

Curated by ChEMBL


Assay Description
Inhibitory activity against VEGFR1


Bioorg Med Chem Lett 16: 2247-51 (2006)


Article DOI: 10.1016/j.bmcl.2006.01.020
BindingDB Entry DOI: 10.7270/Q2NZ8777
More data for this
Ligand-Target Pair
Vascular endothelial growth factor receptor 2


(Mus musculus)
BDBM50181316
PNG
(4-amino-5-(1H-benzo[d]imidazol-2-yl)-1-methyl-1H-p...)
Show SMILES Cn1ncc2c(N)c(-c3nc4ccccc4[nH]3)c(=O)[nH]c12
Show InChI InChI=1S/C14H12N6O/c1-20-13-7(6-16-20)11(15)10(14(21)19-13)12-17-8-4-2-3-5-9(8)18-12/h2-6H,1H3,(H,17,18)(H3,15,19,21)
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PubMed
n/an/a 3.00E+3n/an/an/an/an/an/a



Chiron Corporation

Curated by ChEMBL


Assay Description
Inhibitory activity against VEGFR2


Bioorg Med Chem Lett 16: 2247-51 (2006)


Article DOI: 10.1016/j.bmcl.2006.01.020
BindingDB Entry DOI: 10.7270/Q2NZ8777
More data for this
Ligand-Target Pair
Fibroblast growth factor receptor 1


(Homo sapiens (Human))
BDBM50181316
PNG
(4-amino-5-(1H-benzo[d]imidazol-2-yl)-1-methyl-1H-p...)
Show SMILES Cn1ncc2c(N)c(-c3nc4ccccc4[nH]3)c(=O)[nH]c12
Show InChI InChI=1S/C14H12N6O/c1-20-13-7(6-16-20)11(15)10(14(21)19-13)12-17-8-4-2-3-5-9(8)18-12/h2-6H,1H3,(H,17,18)(H3,15,19,21)
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Article
PubMed
n/an/a 3.00E+3n/an/an/an/an/an/a



Chiron Corporation

Curated by ChEMBL


Assay Description
Inhibitory activity against FGFR1


Bioorg Med Chem Lett 16: 2247-51 (2006)


Article DOI: 10.1016/j.bmcl.2006.01.020
BindingDB Entry DOI: 10.7270/Q2NZ8777
More data for this
Ligand-Target Pair
Platelet-derived growth factor receptor beta


(Mus musculus (mouse))
BDBM50181316
PNG
(4-amino-5-(1H-benzo[d]imidazol-2-yl)-1-methyl-1H-p...)
Show SMILES Cn1ncc2c(N)c(-c3nc4ccccc4[nH]3)c(=O)[nH]c12
Show InChI InChI=1S/C14H12N6O/c1-20-13-7(6-16-20)11(15)10(14(21)19-13)12-17-8-4-2-3-5-9(8)18-12/h2-6H,1H3,(H,17,18)(H3,15,19,21)
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 575n/an/an/an/an/an/a



Chiron Corporation

Curated by ChEMBL


Assay Description
Inhibitory activity against PDGFRbeta


Bioorg Med Chem Lett 16: 2247-51 (2006)


Article DOI: 10.1016/j.bmcl.2006.01.020
BindingDB Entry DOI: 10.7270/Q2NZ8777
More data for this
Ligand-Target Pair