BDBM50181390 2-(1,3-benzothiazol-2-ylsulfanyl)-N-(3-{2,3-dihydrospiro[indene-1,4'-piperidine]-1'-yl}propyl)acetamide::CHEMBL201826

SMILES: O=C(CSc1nc2ccccc2s1)NCCCN1CCC2(CCc3ccccc23)CC1

InChI Key: InChIKey=UWZUEPMEMOCBRG-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50181390   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Nociceptin receptor (Homo sapiens (Human))	BDBM50181390 (2-(1,3-benzothiazol-2-ylsulfanyl)-N-(3-{2,3-dihydr...) Show SMILES O=C(CSc1nc2ccccc2s1)NCCCN1CCC2(CCc3ccccc23)CC1 Show InChI InChI=1S/C25H29N3OS2/c29-23(18-30-24-27-21-8-3-4-9-22(21)31-24)26-14-5-15-28-16-12-25(13-17-28)11-10-19-6-1-2-7-20(19)25/h1-4,6-9H,5,10-18H2,(H,26,29)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	290	n/a	n/a	n/a	n/a	n/a	n/a
Banyu Tsukuba Research Institute Curated by ChEMBL					Assay Description Displacement of [125I]Tyr-nociceptin from cloned human ORL1 expressed in CHO cells				J Med Chem 49: 847-9 (2006) Article DOI: 10.1021/jm0509851 BindingDB Entry DOI: 10.7270/Q2DJ5F78
					More data for this Ligand-Target Pair