BDBM50181500 CHEMBL3817959

SMILES: OCC(=O)NC1CN(N=C1c1ccc(Cl)cc1)C(\Nc1cccc(OC(F)F)c1)=N/C#N

InChI Key: InChIKey=DYLJLPCCRJBRDQ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50181500   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
N-lysine methyltransferase SMYD2 (Homo sapiens (Human))	BDBM50181500 (CHEMBL3817959) Show SMILES OCC(=O)NC1CN(N=C1c1ccc(Cl)cc1)C(\Nc1cccc(OC(F)F)c1)=N/C#N |c:8| Show InChI InChI=1S/C20H17ClF2N6O3/c21-13-6-4-12(5-7-13)18-16(27-17(31)10-30)9-29(28-18)20(25-11-24)26-14-2-1-3-15(8-14)32-19(22)23/h1-8,16,19,30H,9-10H2,(H,25,26)(H,27,31)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.09E+4	n/a	n/a	n/a	n/a	n/a	n/a
BAYER Pharma AG Curated by ChEMBL					Assay Description Inhibition of full length 6xHis-tagged SMYD2 (unknown origin) expressed in Escherichia coli using Btn-Ahx GSRAHSSHLKSKKGQSTSRH-amide as substrate aft...				J Med Chem 59: 4578-600 (2016) BindingDB Entry DOI: 10.7270/Q2RN39S5
					More data for this Ligand-Target Pair