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SMILES: Oc1c(C2=Nc3ccccc3S(=O)(=O)N2)c(=O)n(CCC2CC2)c2c(F)cccc12

InChI Key: InChIKey=WBPYEXYNBVYRRB-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50181656   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
RNA-directed RNA polymerase


(Hepatitis C virus)		BDBM50181656
PNG
(1-(2-cyclopropylethyl)-3-(1,1-dioxo-1,4-dihydroben...)
Show SMILES Oc1c(C2=Nc3ccccc3S(=O)(=O)N2)c(=O)n(CCC2CC2)c2c(F)cccc12 |t:3|
Show InChI InChI=1S/C21H18FN3O4S/c22-14-5-3-4-13-18(14)25(11-10-12-8-9-12)21(27)17(19(13)26)20-23-15-6-1-2-7-16(15)30(28,29)24-20/h1-7,12,26H,8-11H2,(H,23,24)
UniProtKB/TrEMBL

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PC sid
UniChem

Similars
Article
PubMed
n/an/a 90n/an/an/an/an/an/a



GlaxoSmithKline

Curated by ChEMBL


Assay Description
Inhibitory activity against HCV delta 21 NS5B RNA polymerase by SPA assay

J Med Chem 49: 971-83 (2006)


Article DOI: 10.1021/jm050855s
BindingDB Entry DOI: 10.7270/Q2N29WJJ
More data for this
Ligand-Target Pair