BDBM50181763 2-chloro-5-[(2-methyl-4-thiazolyl)ethynyl]pyridine::CHEMBL380848

SMILES: Cc1nc(cs1)C#Cc1ccc(Cl)nc1

InChI Key: InChIKey=PYMPQHSJRUVZKT-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50181763   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50181763 (2-chloro-5-[(2-methyl-4-thiazolyl)ethynyl]pyridine...) Show SMILES Cc1nc(cs1)C#Cc1ccc(Cl)nc1 Show InChI InChI=1S/C11H7ClN2S/c1-8-14-10(7-15-8)4-2-9-3-5-11(12)13-6-9/h3,5-7H,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Activity in agonist-induced phosphoinositide hydrolysis in CHO cells expressing mGluR5a				J Med Chem 49: 1080-100 (2006) Article DOI: 10.1021/jm050570f BindingDB Entry DOI: 10.7270/Q27S7NC5
					More data for this Ligand-Target Pair