BDBM50181954 (S)-5-tert-butyl-1-(3,3-dimethyl-butyl)-3-(1,1-dioxo-1,4-dihydro-1-benzo[1,2,4]thiadiazin-3-yl)-4-hydroxy-1,5-dihydro-pyrrol-2-one::CHEMBL204350

SMILES: CC(C)(C)CCN1[C@H](C(=O)C(C1=O)C1=Nc2ccccc2S(=O)(=O)N1)C(C)(C)C

InChI Key: InChIKey=DZISHBFBPYKEHX-OMOCHNIRSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50181954   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatitis C virus NS5B RNA-dependent RNA polymerase (Hepatitis C virus)	BDBM50181954 ((S)-5-tert-butyl-1-(3,3-dimethyl-butyl)-3-(1,1-dio...) Show SMILES CC(C)(C)CCN1[C@H](C(=O)C(C1=O)C1=Nc2ccccc2S(=O)(=O)N1)C(C)(C)C |t:14| Show InChI InChI=1S/C21H29N3O4S/c1-20(2,3)11-12-24-17(21(4,5)6)16(25)15(19(24)26)18-22-13-9-7-8-10-14(13)29(27,28)23-18/h7-10,15,17H,11-12H2,1-6H3,(H,22,23)/t15?,17-/m1/s1	UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.70	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of HCV NS5B RNA dependent RNA polymerase				Bioorg Med Chem Lett 16: 2205-8 (2006) Article DOI: 10.1016/j.bmcl.2006.01.034 BindingDB Entry DOI: 10.7270/Q26T0M6W
					More data for this Ligand-Target Pair