BDBM50182223 CHEMBL204847::N-((R)-6-((tert-butylamino)methyl)-1,2,3,4-tetrahydronaphthalen-1-yl)-2-((S)-1-(4-methoxyphenylsulfonyl)piperidin-2-yl)acetamide
SMILES: COc1ccc(cc1)S(=O)(=O)N1CCCC[C@H]1CC(=O)N[C@@H]1CCCc2cc(CNC(C)(C)C)ccc12
InChI Key: InChIKey=IDMGNMKRKSUVSK-WNCULLNHSA-N
Data: 2 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Bradykinin B1 receptor (Homo sapiens (Human)) | BDBM50182223 (CHEMBL204847 | N-((R)-6-((tert-butylamino)methyl)-...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 780 | n/a | n/a | n/a | n/a | n/a | n/a |
Amgen Inc. Curated by ChEMBL | Assay Description Inhibition of human B1 receptor | Bioorg Med Chem Lett 16: 2071-5 (2006) Article DOI: 10.1016/j.bmcl.2006.01.069 BindingDB Entry DOI: 10.7270/Q2SN08K7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Bradykinin B1 receptor (Homo sapiens (Human)) | BDBM50182223 (CHEMBL204847 | N-((R)-6-((tert-butylamino)methyl)-...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 1.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Amgen Inc. Curated by ChEMBL | Assay Description Inhibition of human B1 receptor by calcium influx functional assay | Bioorg Med Chem Lett 16: 2071-5 (2006) Article DOI: 10.1016/j.bmcl.2006.01.069 BindingDB Entry DOI: 10.7270/Q2SN08K7 | |||||||||||
More data for this Ligand-Target Pair |