BDBM50185262 (+/-)-2-(2-(1H-indole-2-carboxamido)benzamido)-3-phenylpropanoic acid::2(R,S)-{2-[(1H-indole-2-carbonyl)amino]benzoylamino}-3-phenylpropionic acid::2-(2-(1H-indole-2-carboxamido)benzamido)-3-phenylpropanoic acid::CHEMBL202861
SMILES: OC(=O)C(Cc1ccccc1)NC(=O)c1ccccc1NC(=O)c1cc2ccccc2[nH]1
InChI Key: InChIKey=GXZXQTARIHFJCZ-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Cholecystokinin receptor (Homo sapiens (Human)) | BDBM50185262 ((+/-)-2-(2-(1H-indole-2-carboxamido)benzamido)-3-p...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 59.8 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Trieste Curated by ChEMBL | Assay Description Displacement of [125I]BH-(Thr,-Nle)-CCK-9 from human CCK1 receptor expressed in COS-7 cells after 60 mins by gamma counting | J Med Chem 54: 5769-85 (2011) Article DOI: 10.1021/jm200438b BindingDB Entry DOI: 10.7270/Q2BP036J | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cholecystokinin receptor (Homo sapiens (Human)) | BDBM50185262 ((+/-)-2-(2-(1H-indole-2-carboxamido)benzamido)-3-p...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL | Assay Description Displacement of [125I]CCK-8S from human CCK2R | J Med Chem 49: 6371-90 (2006) Article DOI: 10.1021/jm060590x BindingDB Entry DOI: 10.7270/Q2MK6CHM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cholecystokinin receptor (Homo sapiens (Human)) | BDBM50185262 ((+/-)-2-(2-(1H-indole-2-carboxamido)benzamido)-3-p...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 2.20E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Trieste Curated by ChEMBL | Assay Description Displacement of [125I]BH-(Thr,-Nle)-CCK-9 from human CCK2 receptor expressed in COS-7 cells after 60 mins by gamma counting | J Med Chem 54: 5769-85 (2011) Article DOI: 10.1021/jm200438b BindingDB Entry DOI: 10.7270/Q2BP036J | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cholecystokinin receptor (RAT) | BDBM50185262 ((+/-)-2-(2-(1H-indole-2-carboxamido)benzamido)-3-p...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 197 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Trieste Curated by ChEMBL | Assay Description Displacement of [125I]-BH-CCK8 from CCK1 receptor in Sprague-Dawley rat pancreatic acini after 120 hrs by gamma-counting | J Med Chem 54: 5769-85 (2011) Article DOI: 10.1021/jm200438b BindingDB Entry DOI: 10.7270/Q2BP036J | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cholecystokinin receptor (RAT) | BDBM50185262 ((+/-)-2-(2-(1H-indole-2-carboxamido)benzamido)-3-p...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 197 | n/a | n/a | n/a | n/a | n/a | n/a |
Aristotelian University of Thessaloniki Curated by ChEMBL | Assay Description Displacement of [125I]-CCK8 from CCK1 receptor in rat pancreatic acinar cells | Bioorg Med Chem 17: 5198-206 (2009) Article DOI: 10.1016/j.bmc.2009.05.067 BindingDB Entry DOI: 10.7270/Q2QC03JB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cholecystokinin receptor (RAT) | BDBM50185262 ((+/-)-2-(2-(1H-indole-2-carboxamido)benzamido)-3-p...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 197 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Trieste Curated by ChEMBL | Assay Description Displacement of [125I]BH-CCK8 from CCK1 receptor in Sprague-Dawley rat pancreatic acinar cells | Bioorg Med Chem 17: 2336-50 (2009) Article DOI: 10.1016/j.bmc.2009.02.012 BindingDB Entry DOI: 10.7270/Q27S7NNR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cholecystokinin receptor (Homo sapiens (Human)) | BDBM50185262 ((+/-)-2-(2-(1H-indole-2-carboxamido)benzamido)-3-p...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 197 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Naples Federico II Curated by ChEMBL | Assay Description Displacement of [111In]-DTPAGlu-Gly-[Tyr27(SO3)]-CCK8 from human CCK1 receptor in A431 cells | J Med Chem 49: 2456-62 (2006) Article DOI: 10.1021/jm051050n BindingDB Entry DOI: 10.7270/Q2Q81CPS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cholecystokinin A receptor (Cavia porcellus) | BDBM50185262 ((+/-)-2-(2-(1H-indole-2-carboxamido)benzamido)-3-p...) | PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.64E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Trieste Curated by ChEMBL | Assay Description Displacement of [125I]BH-CCK8 from CCK1 receptor in Hartley guinea pig cerebral cortex | Bioorg Med Chem 17: 2336-50 (2009) Article DOI: 10.1016/j.bmc.2009.02.012 BindingDB Entry DOI: 10.7270/Q27S7NNR | |||||||||||
More data for this Ligand-Target Pair |