BDBM50185357 1-(3-(4-octylphenoxy)-2-oxopropyl)-1H-indole-5-carbaldehyde::1-[3-(4-octylphenoxy)-2-oxopropyl]indole-5-carbaldehyde::CHEMBL409321

SMILES: CCCCCCCCc1ccc(OCC(=O)Cn2ccc3cc(C=O)ccc23)cc1

InChI Key: InChIKey=SPULLVSMHOMOCO-UHFFFAOYSA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50185357   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cPLA2 C2 (Homo sapiens (Human))	BDBM50185357 (1-(3-(4-octylphenoxy)-2-oxopropyl)-1H-indole-5-car...) Show SMILES CCCCCCCCc1ccc(OCC(=O)Cn2ccc3cc(C=O)ccc23)cc1 Show InChI InChI=1S/C26H31NO3/c1-2-3-4-5-6-7-8-21-9-12-25(13-10-21)30-20-24(29)18-27-16-15-23-17-22(19-28)11-14-26(23)27/h9-17,19H,2-8,18,20H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Münster Curated by ChEMBL					Assay Description Inhibition of human isolated cPLA2alpha by vescicle assay				J Med Chem 49: 2611-20 (2006) Article DOI: 10.1021/jm051243a BindingDB Entry DOI: 10.7270/Q2668CSF
					More data for this Ligand-Target Pair
cPLA2 C2 (Homo sapiens (Human))	BDBM50185357 (1-(3-(4-octylphenoxy)-2-oxopropyl)-1H-indole-5-car...) Show SMILES CCCCCCCCc1ccc(OCC(=O)Cn2ccc3cc(C=O)ccc23)cc1 Show InChI InChI=1S/C26H31NO3/c1-2-3-4-5-6-7-8-21-9-12-25(13-10-21)30-20-24(29)18-27-16-15-23-17-22(19-28)11-14-26(23)27/h9-17,19H,2-8,18,20H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of M£nster Curated by ChEMBL					Assay Description Inhibition of cPLA2 from human platelets by RP-HPLC				Bioorg Med Chem 18: 945-52 (2010) Article DOI: 10.1016/j.bmc.2009.11.028 BindingDB Entry DOI: 10.7270/Q2N016MF
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 (aa 30-579) (Rattus norvegicus (rat))	BDBM50185357 (1-(3-(4-octylphenoxy)-2-oxopropyl)-1H-indole-5-car...) Show SMILES CCCCCCCCc1ccc(OCC(=O)Cn2ccc3cc(C=O)ccc23)cc1 Show InChI InChI=1S/C26H31NO3/c1-2-3-4-5-6-7-8-21-9-12-25(13-10-21)30-20-24(29)18-27-16-15-23-17-22(19-28)11-14-26(23)27/h9-17,19H,2-8,18,20H2,1H3	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of M£nster Curated by ChEMBL					Assay Description Inhibition of FAAH from rat brain microsomes by RP-HPLC				Bioorg Med Chem 18: 945-52 (2010) Article DOI: 10.1016/j.bmc.2009.11.028 BindingDB Entry DOI: 10.7270/Q2N016MF
					More data for this Ligand-Target Pair
cPLA2 C2 (Homo sapiens (Human))	BDBM50185357 (1-(3-(4-octylphenoxy)-2-oxopropyl)-1H-indole-5-car...) Show SMILES CCCCCCCCc1ccc(OCC(=O)Cn2ccc3cc(C=O)ccc23)cc1 Show InChI InChI=1S/C26H31NO3/c1-2-3-4-5-6-7-8-21-9-12-25(13-10-21)30-20-24(29)18-27-16-15-23-17-22(19-28)11-14-26(23)27/h9-17,19H,2-8,18,20H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Münster Curated by ChEMBL					Assay Description Inhibition of cPLA2alpha activity assessed by A23187-induced arachidonic acid release in human platelet				J Med Chem 49: 2611-20 (2006) Article DOI: 10.1021/jm051243a BindingDB Entry DOI: 10.7270/Q2668CSF
					More data for this Ligand-Target Pair