Found 5 hits for monomerid = 50185463 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kcal/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Integrin alpha-V/beta-3
(Homo sapiens (Human)) | BDBM50185463
(3-(benzo[d][1,3]dioxol-5-yl)-4-(1-phenyl-5-(2-(5,6...)Show SMILES OC(=O)CC(Cc1cc(OCCc2ccc3CCCNc3n2)n(n1)-c1ccccc1)c1ccc2OCOc2c1 Show InChI InChI=1S/C30H30N4O5/c35-29(36)17-22(21-9-11-26-27(16-21)39-19-38-26)15-24-18-28(34(33-24)25-6-2-1-3-7-25)37-14-12-23-10-8-20-5-4-13-31-30(20)32-23/h1-3,6-11,16,18,22H,4-5,12-15,17,19H2,(H,31,32)(H,35,36) | PDB
UniProtKB/SwissProt
antibodypedia
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 1.40 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Inhibition of alphavbeta3 integrin by SPRA |
Bioorg Med Chem Lett 16: 3156-61 (2006)
Article DOI: 10.1016/j.bmcl.2006.03.045
BindingDB Entry DOI: 10.7270/Q29023CB |
More data for this
Ligand-Target Pair | |
Integrin alpha-V/beta-3
(Homo sapiens (Human)) | BDBM50185463
(3-(benzo[d][1,3]dioxol-5-yl)-4-(1-phenyl-5-(2-(5,6...)Show SMILES OC(=O)CC(Cc1cc(OCCc2ccc3CCCNc3n2)n(n1)-c1ccccc1)c1ccc2OCOc2c1 Show InChI InChI=1S/C30H30N4O5/c35-29(36)17-22(21-9-11-26-27(16-21)39-19-38-26)15-24-18-28(34(33-24)25-6-2-1-3-7-25)37-14-12-23-10-8-20-5-4-13-31-30(20)32-23/h1-3,6-11,16,18,22H,4-5,12-15,17,19H2,(H,31,32)(H,35,36) | PDB
UniProtKB/SwissProt
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 1.18 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Inhibition of alphavbeta3 integrin in 293 cells |
Bioorg Med Chem Lett 16: 3156-61 (2006)
Article DOI: 10.1016/j.bmcl.2006.03.045
BindingDB Entry DOI: 10.7270/Q29023CB |
More data for this
Ligand-Target Pair | |
Integrin alpha-IIb/beta-3
(Homo sapiens (Human)) | BDBM50185463
(3-(benzo[d][1,3]dioxol-5-yl)-4-(1-phenyl-5-(2-(5,6...)Show SMILES OC(=O)CC(Cc1cc(OCCc2ccc3CCCNc3n2)n(n1)-c1ccccc1)c1ccc2OCOc2c1 Show InChI InChI=1S/C30H30N4O5/c35-29(36)17-22(21-9-11-26-27(16-21)39-19-38-26)15-24-18-28(34(33-24)25-6-2-1-3-7-25)37-14-12-23-10-8-20-5-4-13-31-30(20)32-23/h1-3,6-11,16,18,22H,4-5,12-15,17,19H2,(H,31,32)(H,35,36) | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 24.4 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Inhibition of alpha2bbeta3 integrin by SPRA |
Bioorg Med Chem Lett 16: 3156-61 (2006)
Article DOI: 10.1016/j.bmcl.2006.03.045
BindingDB Entry DOI: 10.7270/Q29023CB |
More data for this
Ligand-Target Pair | |
Integrin alpha-V/beta-6
(Homo sapiens (Human)) | BDBM50185463
(3-(benzo[d][1,3]dioxol-5-yl)-4-(1-phenyl-5-(2-(5,6...)Show SMILES OC(=O)CC(Cc1cc(OCCc2ccc3CCCNc3n2)n(n1)-c1ccccc1)c1ccc2OCOc2c1 Show InChI InChI=1S/C30H30N4O5/c35-29(36)17-22(21-9-11-26-27(16-21)39-19-38-26)15-24-18-28(34(33-24)25-6-2-1-3-7-25)37-14-12-23-10-8-20-5-4-13-31-30(20)32-23/h1-3,6-11,16,18,22H,4-5,12-15,17,19H2,(H,31,32)(H,35,36) | PDB
UniProtKB/SwissProt
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 352 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Inhibition of alphavbeta6 integrin in HT29 cells |
Bioorg Med Chem Lett 16: 3156-61 (2006)
Article DOI: 10.1016/j.bmcl.2006.03.045
BindingDB Entry DOI: 10.7270/Q29023CB |
More data for this
Ligand-Target Pair | |
Integrin alpha-V/beta-5
(Homo sapiens (Human)) | BDBM50185463
(3-(benzo[d][1,3]dioxol-5-yl)-4-(1-phenyl-5-(2-(5,6...)Show SMILES OC(=O)CC(Cc1cc(OCCc2ccc3CCCNc3n2)n(n1)-c1ccccc1)c1ccc2OCOc2c1 Show InChI InChI=1S/C30H30N4O5/c35-29(36)17-22(21-9-11-26-27(16-21)39-19-38-26)15-24-18-28(34(33-24)25-6-2-1-3-7-25)37-14-12-23-10-8-20-5-4-13-31-30(20)32-23/h1-3,6-11,16,18,22H,4-5,12-15,17,19H2,(H,31,32)(H,35,36) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 3.27 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Inhibition of alphavbeta5 integrin in 293 cells |
Bioorg Med Chem Lett 16: 3156-61 (2006)
Article DOI: 10.1016/j.bmcl.2006.03.045
BindingDB Entry DOI: 10.7270/Q29023CB |
More data for this
Ligand-Target Pair | |
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