null

SMILES: CN1CCC(CC1)c1cccc2[nH]c(cc12)-c1nc(CCc2ccc(Cl)cc2)no1

InChI Key: InChIKey=XRRSGVAKNLABMJ-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50185544   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Nociceptin receptor (Homo sapiens (Human))	BDBM50185544 (2-(3-(4-chlorophenethyl)-1,2,4-oxadiazol-5-yl)-4-(...) Show SMILES CN1CCC(CC1)c1cccc2[nH]c(cc12)-c1nc(CCc2ccc(Cl)cc2)no1 Show InChI InChI=1S/C24H25ClN4O/c1-29-13-11-17(12-14-29)19-3-2-4-21-20(19)15-22(26-21)24-27-23(28-30-24)10-7-16-5-8-18(25)9-6-16/h2-6,8-9,15,17,26H,7,10-14H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	899	n/a	n/a	n/a	n/a	n/a	n/a
Banyu Tsukuba Research Institute Curated by ChEMBL					Assay Description Antagonist activity against ORL1 receptor by GTPgammaS assay				Bioorg Med Chem Lett 16: 3569-73 (2006) Article DOI: 10.1016/j.bmcl.2006.03.086 BindingDB Entry DOI: 10.7270/Q2N879D1
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM50185544 (2-(3-(4-chlorophenethyl)-1,2,4-oxadiazol-5-yl)-4-(...) Show SMILES CN1CCC(CC1)c1cccc2[nH]c(cc12)-c1nc(CCc2ccc(Cl)cc2)no1 Show InChI InChI=1S/C24H25ClN4O/c1-29-13-11-17(12-14-29)19-3-2-4-21-20(19)15-22(26-21)24-27-23(28-30-24)10-7-16-5-8-18(25)9-6-16/h2-6,8-9,15,17,26H,7,10-14H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	62	n/a	n/a	n/a	n/a	n/a	n/a
Banyu Tsukuba Research Institute Curated by ChEMBL					Assay Description Displacement of [125I][Tyr14]N/OFQ from ORL1 receptor transfected in CHO cells				Bioorg Med Chem Lett 16: 3569-73 (2006) Article DOI: 10.1016/j.bmcl.2006.03.086 BindingDB Entry DOI: 10.7270/Q2N879D1
					More data for this Ligand-Target Pair