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SMILES: COc1c(C)c2COC(=O)c2c(O)c1C\C=C(/C)CN(CCP(O)(O)=O)C=O

InChI Key: InChIKey=OCFISPPMRUERDI-NYYWCZLTSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50185597   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Inosine-5'-monophosphate dehydrogenase 2


(Homo sapiens (Human))		BDBM50185597
PNG
((E)-2-(N-(4-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1,...)
Show SMILES COc1c(C)c2COC(=O)c2c(O)c1C\C=C(/C)CN(CCP(O)(O)=O)C=O
Show InChI InChI=1S/C18H24NO8P/c1-11(8-19(10-20)6-7-28(23,24)25)4-5-13-16(21)15-14(9-27-18(15)22)12(2)17(13)26-3/h4,10,21H,5-9H2,1-3H3,(H2,23,24,25)/b11-4+
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n/an/a 749n/an/an/an/an/an/a



Gilead Sciences, Inc.

Curated by ChEMBL


Assay Description
Inhibition of human IMPDH2

Bioorg Med Chem Lett 16: 3479-83 (2006)


Article DOI: 10.1016/j.bmcl.2006.03.097
BindingDB Entry DOI: 10.7270/Q2HH6JP9
More data for this
Ligand-Target Pair