BDBM50186872 CHEMBL376936::N-{(R)-1-(4-chloro-benzyl)-2-[4-(1-methyl-4-phenyl-piperidin-4-yl)-piperazin-1-yl]-2-oxo-ethyl}-2-(2,3-dihydro-1H-isoindol-1-yl)-acetamide trifluoroacetic acid

SMILES: CN1CCC(CC1)(N1CCN(CC1)C(=O)[C@@H](Cc1ccc(Cl)cc1)NC(=O)CC1NCc2ccccc12)c1ccccc1

InChI Key: InChIKey=TVYHNAAZQNGNOW-IADGFXSZSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50186872   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Melanocortin receptor 4 (Homo sapiens (Human))	BDBM50186872 (CHEMBL376936 | N-{(R)-1-(4-chloro-benzyl)-2-[4-(1-...) Show SMILES CN1CCC(CC1)(N1CCN(CC1)C(=O)[C@@H](Cc1ccc(Cl)cc1)NC(=O)CC1NCc2ccccc12)c1ccccc1 Show InChI InChI=1S/C35H42ClN5O2/c1-39-17-15-35(16-18-39,28-8-3-2-4-9-28)41-21-19-40(20-22-41)34(43)32(23-26-11-13-29(36)14-12-26)38-33(42)24-31-30-10-6-5-7-27(30)25-37-31/h2-14,31-32,37H,15-25H2,1H3,(H,38,42)/t31?,32-/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	215	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Displacement of [125I]NDP-alpha-MSH from human MC4 receptor transfected in HEK293 cells				Bioorg Med Chem Lett 16: 3843-6 (2006) Article DOI: 10.1016/j.bmcl.2006.04.016 BindingDB Entry DOI: 10.7270/Q2SQ900D
					More data for this Ligand-Target Pair