BDBM50187562 CHEMBL3827593

SMILES: Clc1cccc(c1)C(=O)NC(=S)Nc1ccc(Cl)cc1Cl

InChI Key: InChIKey=PVEPTSNJPWLFHR-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50187562   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Urease (Canavalia ensiformis (Jack bean) (Horse bean))	BDBM50187562 (CHEMBL3827593) Show SMILES Clc1cccc(c1)C(=O)NC(=S)Nc1ccc(Cl)cc1Cl Show InChI InChI=1S/C14H9Cl3N2OS/c15-9-3-1-2-8(6-9)13(20)19-14(21)18-12-5-4-10(16)7-11(12)17/h1-7H,(H2,18,19,20,21)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	1.34E+3	n/a	n/a	n/a	n/a	n/a	n/a
Quaid-i-Azam University Curated by ChEMBL					Assay Description Inhibition of jack bean urease using urea as substrate assessed as reduction in ammonia production after 30 mins by indophenol method				Bioorg Med Chem 24: 4452-4463 (2016) BindingDB Entry DOI: 10.7270/Q2VX0JF4
					More data for this Ligand-Target Pair