BDBM50188382 2,3-dioxo-1-propylindoline-5-carboxamide::CHEMBL210525
SMILES: CCCN1C(=O)C(=O)c2cc(ccc12)C(N)=O
InChI Key: InChIKey=UPFRLUKDHMINPH-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50188382 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Papain-like protease (PLpro)
(Human SARS coronavirus (SARS-CoV)) | BDBM50188382
(2,3-dioxo-1-propylindoline-5-carboxamide | CHEMBL2...)Show InChI InChI=1S/C12H12N2O3/c1-2-5-14-9-4-3-7(11(13)16)6-8(9)10(15)12(14)17/h3-4,6H,2,5H2,1H3,(H2,13,16) | PDB
UniProtKB/SwissProt UniProtKB/TrEMBL
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 2.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Peking University
Curated by ChEMBL
| Assay Description Inhibition of SARS CoV 3C-like protease |
J Med Chem 49: 3440-3 (2006)
Article DOI: 10.1021/jm0602357 BindingDB Entry DOI: 10.7270/Q2TD9WZX |
More data for this Ligand-Target Pair | |
Replicase polyprotein 1ab
(2019-nCoV) | BDBM50188382
(2,3-dioxo-1-propylindoline-5-carboxamide | CHEMBL2...)Show InChI InChI=1S/C12H12N2O3/c1-2-5-14-9-4-3-7(11(13)16)6-8(9)10(15)12(14)17/h3-4,6H,2,5H2,1H3,(H2,13,16) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| | n/a | n/a | 1.02E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this Ligand-Target Pair | |
3C-like proteinase (3CL-PRO)
(Human SARS coronavirus (SARS-CoV) (Severe acute re...) | BDBM50188382
(2,3-dioxo-1-propylindoline-5-carboxamide | CHEMBL2...)Show InChI InChI=1S/C12H12N2O3/c1-2-5-14-9-4-3-7(11(13)16)6-8(9)10(15)12(14)17/h3-4,6H,2,5H2,1H3,(H2,13,16) | PDB MMDB
KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| | n/a | n/a | 2.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this Ligand-Target Pair | |