BDBM50189304 CHEMBL3827991

SMILES: CCOC(=O)c1cc(C(=O)\C=C\c2ccc(Br)cc2)n2ccc(OC)cc12

InChI Key: InChIKey=DZAIAPALPTXITL-RMKNXTFCSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50189304   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein Farnesyltransferase (PFT) (Homo sapiens (Human))	BDBM50189304 (CHEMBL3827991) Show SMILES CCOC(=O)c1cc(C(=O)\C=C\c2ccc(Br)cc2)n2ccc(OC)cc12 Show InChI InChI=1S/C21H18BrNO4/c1-3-27-21(25)17-13-19(23-11-10-16(26-2)12-18(17)23)20(24)9-6-14-4-7-15(22)8-5-14/h4-13H,3H2,1-2H3/b9-6+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	602	n/a	n/a	n/a	n/a	n/a	n/a
'Alexandru Ioan Cuza' University of Iasi Curated by ChEMBL					Assay Description Inhibition of human recombinant farnesyltransferase using farnesylpyrophosphate and dansyl-GCVLS as substrate measured for 15 mins by fluorescence as...				Bioorg Med Chem Lett 26: 3730-4 (2016) BindingDB Entry DOI: 10.7270/Q2DR2XFP
					More data for this Ligand-Target Pair