BDBM50190257 CHEMBL3828150

SMILES: COc1ccccc1Nc1nnc(Cn2c(C)nc3ccccc23)s1

InChI Key: InChIKey=JJLQCGLAWNTTSY-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50190257   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM50190257 (CHEMBL3828150) Show SMILES COc1ccccc1Nc1nnc(Cn2c(C)nc3ccccc23)s1 Show InChI InChI=1S/C18H17N5OS/c1-12-19-13-7-3-5-9-15(13)23(12)11-17-21-22-18(25-17)20-14-8-4-6-10-16(14)24-2/h3-10H,11H2,1-2H3,(H,20,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	184	n/a	n/a	n/a	n/a	n/a	n/a
Jamia Hamdard (Hamdard University) Curated by ChEMBL					Assay Description Inhibition of recombinant human N-terminal His-tagged GSK-3beta expressed in Escherichia coli using glycogen synthase-2 as substrate and ATP measured...				Bioorg Med Chem Lett 26: 4020-4 (2016) BindingDB Entry DOI: 10.7270/Q2639RP0
					More data for this Ligand-Target Pair