BDBM50190342 CHEMBL3828713
SMILES: CN1C(=S)N(C(=O)\C1=C\c1ccc(O)cc1O)c1ccc(C)cc1
InChI Key: InChIKey=KWRHTPOCHZBICN-DHDCSXOGSA-N
Data: 2 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
NADPH oxidase 1 (Homo sapiens (Human)) | BDBM50190342 (CHEMBL3828713) | KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 2.71E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Ewha Womans University Curated by ChEMBL | Assay Description Inhibition of human NOX1 expressed in Drosophila DUOX knockdown model assessed as decrease in ROS production by lucigenin chemiluminescence assay | Bioorg Med Chem 24: 4144-4151 (2016) BindingDB Entry DOI: 10.7270/Q2XK8HHT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
NADPH oxidase 4 (Homo sapiens (Human)) | BDBM50190342 (CHEMBL3828713) | KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 3.46E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Ewha Womans University Curated by ChEMBL | Assay Description Inhibition of human NOX4 expressed in Drosophila DUOX knockdown model assessed as decrease in ROS production by lucigenin chemiluminescence assay | Bioorg Med Chem 24: 4144-4151 (2016) BindingDB Entry DOI: 10.7270/Q2XK8HHT | |||||||||||
More data for this Ligand-Target Pair |