BDBM50190500 6-chloro-3-(1-methyl-1-phenylethyl)amino-4H-thieno[3,2-e]-1,2,4-thiadiazine 1,1-dioxide::CHEMBL212041

SMILES: CC(C)(NC1=Nc2cc(Cl)sc2S(=O)(=O)N1)c1ccccc1

InChI Key: InChIKey=XUSQKHZVTSWKMN-UHFFFAOYSA-N

Data: 2 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50190500   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Potassium channel, inwardly rectifying, subfamily J, member 11/Sulfonylurea receptor 1 (Homo sapiens (Human))	BDBM50190500 (6-chloro-3-(1-methyl-1-phenylethyl)amino-4H-thieno...) Show SMILES CC(C)(NC1=Nc2cc(Cl)sc2S(=O)(=O)N1)c1ccccc1 |t:4| Show InChI InChI=1S/C14H14ClN3O2S2/c1-14(2,9-6-4-3-5-7-9)17-13-16-10-8-11(15)21-12(10)22(19,20)18-13/h3-8H,1-2H3,(H2,16,17,18)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.60E+5	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]glibenclamide from human Kir6.2/SUR1 expressed in HEK293 cells				J Med Chem 49: 4127-39 (2006) Article DOI: 10.1021/jm060042j BindingDB Entry DOI: 10.7270/Q2B27TWN
					More data for this Ligand-Target Pair
Potassium channel, inwardly rectifying, subfamily J, member 11/Sulfonylurea receptor 1 (Homo sapiens (Human))	BDBM50190500 (6-chloro-3-(1-methyl-1-phenylethyl)amino-4H-thieno...) Show SMILES CC(C)(NC1=Nc2cc(Cl)sc2S(=O)(=O)N1)c1ccccc1 |t:4| Show InChI InChI=1S/C14H14ClN3O2S2/c1-14(2,9-6-4-3-5-7-9)17-13-16-10-8-11(15)21-12(10)22(19,20)18-13/h3-8H,1-2H3,(H2,16,17,18)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	81	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]glibenclamide from human Kir6.2/SUR1 expressed in HEK293 cells in presence of 2 mM ATP				J Med Chem 49: 4127-39 (2006) Article DOI: 10.1021/jm060042j BindingDB Entry DOI: 10.7270/Q2B27TWN
					More data for this Ligand-Target Pair
Potassium channel, inwardly rectifying, subfamily J, member 11/Sulfonylurea receptor 1 (Homo sapiens (Human))	BDBM50190500 (6-chloro-3-(1-methyl-1-phenylethyl)amino-4H-thieno...) Show SMILES CC(C)(NC1=Nc2cc(Cl)sc2S(=O)(=O)N1)c1ccccc1 |t:4| Show InChI InChI=1S/C14H14ClN3O2S2/c1-14(2,9-6-4-3-5-7-9)17-13-16-10-8-11(15)21-12(10)22(19,20)18-13/h3-8H,1-2H3,(H2,16,17,18)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	180	n/a	n/a	n/a	n/a
Novo Nordisk Research and Development Curated by ChEMBL					Assay Description Repolarization of HEK293 cells expressing Kir6.2/SUR1 KATP channels				J Med Chem 49: 4127-39 (2006) Article DOI: 10.1021/jm060042j BindingDB Entry DOI: 10.7270/Q2B27TWN
					More data for this Ligand-Target Pair