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SMILES: Clc1ncc(Br)c(n1)N1CCN(CC1)S(=O)(=O)c1ccc(cc1)-c1ccccc1

InChI Key: InChIKey=RSMXWAAHBXSACS-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50190683   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Breakpoint cluster region protein/Tyrosine-protein kinase ABL1


(Homo sapiens (Human))		BDBM50190683
PNG
(CHEMBL3956666)
Show SMILES Clc1ncc(Br)c(n1)N1CCN(CC1)S(=O)(=O)c1ccc(cc1)-c1ccccc1
Show InChI InChI=1S/C20H18BrClN4O2S/c21-18-14-23-20(22)24-19(18)25-10-12-26(13-11-25)29(27,28)17-8-6-16(7-9-17)15-4-2-1-3-5-15/h1-9,14H,10-13H2
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MMDB

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PC cid
PC sid
UniChem

Similars
PubMed
n/an/a 640n/an/an/an/an/an/a



Rallis India Limited

Curated by ChEMBL


Assay Description
Inhibition of BRC/ABL1 (unknown origin) after 40 mins by ADP-Glo assay

Eur J Med Chem 119: 70-82 (2016)


BindingDB Entry DOI: 10.7270/Q2445PDS
More data for this
Ligand-Target Pair