BDBM50191560 (S)-2-acetamido-N1-((R)-1-((2S,4S)-2-(3-guanidinopropyl)-4-(naphthalen-2-ylmethoxy)pyrrolidin-1-yl)-1-oxo-3-phenylpropan-2-yl)pentanediamide::CHEMBL209622

SMILES: [#7]-[#6@@H](-[#6]-[#6](-[#7])=O)-[#6](=O)-[#7]-[#6@H](-[#6]-c1ccccc1)-[#6](=O)-[#7]-1-[#6]-[#6@H](-[#6]-[#6@@H]-1-[#6]-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])-[#8]-[#6]-c1ccc2ccccc2c1

InChI Key: InChIKey=MNJTTYMJKZNPFK-LAJGZZDBSA-N

Data: 3 KI  3 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50191560   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Melanocyte-stimulating hormone receptor (Homo sapiens (Human))	BDBM50191560 ((S)-2-acetamido-N1-((R)-1-((2S,4S)-2-(3-guanidinop...) Show SMILES [#7]-[#6@@H](-[#6]-[#6](-[#7])=O)-[#6](=O)-[#7]-[#6@H](-[#6]-c1ccccc1)-[#6](=O)-[#7]-1-[#6]-[#6@H](-[#6]-[#6@@H]-1-[#6]-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])-[#8]-[#6]-c1ccc2ccccc2c1 Show InChI InChI=1S/C32H41N7O4/c33-27(18-29(34)40)30(41)38-28(16-21-7-2-1-3-8-21)31(42)39-19-26(17-25(39)11-6-14-37-32(35)36)43-20-22-12-13-23-9-4-5-10-24(23)15-22/h1-5,7-10,12-13,15,25-28H,6,11,14,16-20,33H2,(H2,34,40)(H,38,41)(H4,35,36,37)/t25-,26-,27-,28+/m0/s1	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	103	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Procter & Gamble Pharmaceuticals Curated by ChEMBL					Assay Description Displacement of europium labeled NDP-alpha-MSH from human MC1R expressed in HEK293 cells				J Med Chem 49: 4745-61 (2006) Article DOI: 10.1021/jm060384p BindingDB Entry DOI: 10.7270/Q29W0F4J
					More data for this Ligand-Target Pair
Melanocortin receptor 4 (Homo sapiens (Human))	BDBM50191560 ((S)-2-acetamido-N1-((R)-1-((2S,4S)-2-(3-guanidinop...) Show SMILES [#7]-[#6@@H](-[#6]-[#6](-[#7])=O)-[#6](=O)-[#7]-[#6@H](-[#6]-c1ccccc1)-[#6](=O)-[#7]-1-[#6]-[#6@H](-[#6]-[#6@@H]-1-[#6]-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])-[#8]-[#6]-c1ccc2ccccc2c1 Show InChI InChI=1S/C32H41N7O4/c33-27(18-29(34)40)30(41)38-28(16-21-7-2-1-3-8-21)31(42)39-19-26(17-25(39)11-6-14-37-32(35)36)43-20-22-12-13-23-9-4-5-10-24(23)15-22/h1-5,7-10,12-13,15,25-28H,6,11,14,16-20,33H2,(H2,34,40)(H,38,41)(H4,35,36,37)/t25-,26-,27-,28+/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	187	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Procter & Gamble Pharmaceuticals Curated by ChEMBL					Assay Description Displacement of europium labeled NDP-alpha-MSH from human MC4R expressed in HEK293 cells				J Med Chem 49: 4745-61 (2006) Article DOI: 10.1021/jm060384p BindingDB Entry DOI: 10.7270/Q29W0F4J
					More data for this Ligand-Target Pair
Melanocortin receptor 3 (Homo sapiens (Human))	BDBM50191560 ((S)-2-acetamido-N1-((R)-1-((2S,4S)-2-(3-guanidinop...) Show SMILES [#7]-[#6@@H](-[#6]-[#6](-[#7])=O)-[#6](=O)-[#7]-[#6@H](-[#6]-c1ccccc1)-[#6](=O)-[#7]-1-[#6]-[#6@H](-[#6]-[#6@@H]-1-[#6]-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])-[#8]-[#6]-c1ccc2ccccc2c1 Show InChI InChI=1S/C32H41N7O4/c33-27(18-29(34)40)30(41)38-28(16-21-7-2-1-3-8-21)31(42)39-19-26(17-25(39)11-6-14-37-32(35)36)43-20-22-12-13-23-9-4-5-10-24(23)15-22/h1-5,7-10,12-13,15,25-28H,6,11,14,16-20,33H2,(H2,34,40)(H,38,41)(H4,35,36,37)/t25-,26-,27-,28+/m0/s1	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	835	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Procter & Gamble Pharmaceuticals Curated by ChEMBL					Assay Description Displacement of europium labeled NDP-alpha-MSH from human MC3R expressed in HEK293 cells				J Med Chem 49: 4745-61 (2006) Article DOI: 10.1021/jm060384p BindingDB Entry DOI: 10.7270/Q29W0F4J
					More data for this Ligand-Target Pair
Melanocortin receptor 4 (Homo sapiens (Human))	BDBM50191560 ((S)-2-acetamido-N1-((R)-1-((2S,4S)-2-(3-guanidinop...) Show SMILES [#7]-[#6@@H](-[#6]-[#6](-[#7])=O)-[#6](=O)-[#7]-[#6@H](-[#6]-c1ccccc1)-[#6](=O)-[#7]-1-[#6]-[#6@H](-[#6]-[#6@@H]-1-[#6]-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])-[#8]-[#6]-c1ccc2ccccc2c1 Show InChI InChI=1S/C32H41N7O4/c33-27(18-29(34)40)30(41)38-28(16-21-7-2-1-3-8-21)31(42)39-19-26(17-25(39)11-6-14-37-32(35)36)43-20-22-12-13-23-9-4-5-10-24(23)15-22/h1-5,7-10,12-13,15,25-28H,6,11,14,16-20,33H2,(H2,34,40)(H,38,41)(H4,35,36,37)/t25-,26-,27-,28+/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	8	n/a	n/a	n/a	n/a
Procter & Gamble Pharmaceuticals Curated by ChEMBL					Assay Description Agonist activity at human MC4R transfected in HEK293 cells				J Med Chem 49: 4745-61 (2006) Article DOI: 10.1021/jm060384p BindingDB Entry DOI: 10.7270/Q29W0F4J
					More data for this Ligand-Target Pair
Melanocyte-stimulating hormone receptor (Homo sapiens (Human))	BDBM50191560 ((S)-2-acetamido-N1-((R)-1-((2S,4S)-2-(3-guanidinop...) Show SMILES [#7]-[#6@@H](-[#6]-[#6](-[#7])=O)-[#6](=O)-[#7]-[#6@H](-[#6]-c1ccccc1)-[#6](=O)-[#7]-1-[#6]-[#6@H](-[#6]-[#6@@H]-1-[#6]-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])-[#8]-[#6]-c1ccc2ccccc2c1 Show InChI InChI=1S/C32H41N7O4/c33-27(18-29(34)40)30(41)38-28(16-21-7-2-1-3-8-21)31(42)39-19-26(17-25(39)11-6-14-37-32(35)36)43-20-22-12-13-23-9-4-5-10-24(23)15-22/h1-5,7-10,12-13,15,25-28H,6,11,14,16-20,33H2,(H2,34,40)(H,38,41)(H4,35,36,37)/t25-,26-,27-,28+/m0/s1	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	4.30	n/a	n/a	n/a	n/a
Procter & Gamble Pharmaceuticals Curated by ChEMBL					Assay Description Agonist activity at human MC1R transfected in HEK293 cells				J Med Chem 49: 4745-61 (2006) Article DOI: 10.1021/jm060384p BindingDB Entry DOI: 10.7270/Q29W0F4J
					More data for this Ligand-Target Pair
Melanocortin receptor 3 (Homo sapiens (Human))	BDBM50191560 ((S)-2-acetamido-N1-((R)-1-((2S,4S)-2-(3-guanidinop...) Show SMILES [#7]-[#6@@H](-[#6]-[#6](-[#7])=O)-[#6](=O)-[#7]-[#6@H](-[#6]-c1ccccc1)-[#6](=O)-[#7]-1-[#6]-[#6@H](-[#6]-[#6@@H]-1-[#6]-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])-[#8]-[#6]-c1ccc2ccccc2c1 Show InChI InChI=1S/C32H41N7O4/c33-27(18-29(34)40)30(41)38-28(16-21-7-2-1-3-8-21)31(42)39-19-26(17-25(39)11-6-14-37-32(35)36)43-20-22-12-13-23-9-4-5-10-24(23)15-22/h1-5,7-10,12-13,15,25-28H,6,11,14,16-20,33H2,(H2,34,40)(H,38,41)(H4,35,36,37)/t25-,26-,27-,28+/m0/s1	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	10	n/a	n/a	n/a	n/a
Procter & Gamble Pharmaceuticals Curated by ChEMBL					Assay Description Agonist activity at human MC3R transfected in HEK293 cells				J Med Chem 49: 4745-61 (2006) Article DOI: 10.1021/jm060384p BindingDB Entry DOI: 10.7270/Q29W0F4J
					More data for this Ligand-Target Pair