BDBM50192107 CHEMBL211921::pyridine-3-carboxylic acid guanidino-[4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-phenyl]-methyl ester trifluoro-acetic acid

SMILES: [#6]C1([#6])[#8]-[#5](-[#8]C1([#6])[#6])-c1ccc(cc1)-[#6](-[#8]-[#6](=O)-c1cccnc1)\[#7]=[#6](\[#7])-[#7]

InChI Key: InChIKey=ZOIWSYXTVCLIGD-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50192107   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation factor X (Homo sapiens (Human))	BDBM50192107 (CHEMBL211921 | pyridine-3-carboxylic acid guanidin...) Show SMILES [#6]C1([#6])[#8]-[#5](-[#8]C1([#6])[#6])-c1ccc(cc1)-[#6](-[#8]-[#6](=O)-c1cccnc1)\[#7]=[#6](\[#7])-[#7] Show InChI InChI=1S/C20H25BN4O4/c1-19(2)20(3,4)29-21(28-19)15-9-7-13(8-10-15)16(25-18(22)23)27-17(26)14-6-5-11-24-12-14/h5-12,16H,1-4H3,(H4,22,23,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.36E+4	n/a	n/a	n/a	n/a	n/a	n/a
Daiichi Asubio Medical Research Laboratories, LLC Curated by ChEMBL					Assay Description Inhibition of f10a				Bioorg Med Chem Lett 16: 5022-7 (2006) Article DOI: 10.1016/j.bmcl.2006.07.043 BindingDB Entry DOI: 10.7270/Q2PV6M5D
					More data for this Ligand-Target Pair
Coagulation factor XI (Homo sapiens (Human))	BDBM50192107 (CHEMBL211921 | pyridine-3-carboxylic acid guanidin...) Show SMILES [#6]C1([#6])[#8]-[#5](-[#8]C1([#6])[#6])-c1ccc(cc1)-[#6](-[#8]-[#6](=O)-c1cccnc1)\[#7]=[#6](\[#7])-[#7] Show InChI InChI=1S/C20H25BN4O4/c1-19(2)20(3,4)29-21(28-19)15-9-7-13(8-10-15)16(25-18(22)23)27-17(26)14-6-5-11-24-12-14/h5-12,16H,1-4H3,(H4,22,23,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Daiichi Asubio Medical Research Laboratories, LLC Curated by ChEMBL					Assay Description Inhibition of f11a				Bioorg Med Chem Lett 16: 5022-7 (2006) Article DOI: 10.1016/j.bmcl.2006.07.043 BindingDB Entry DOI: 10.7270/Q2PV6M5D
					More data for this Ligand-Target Pair
Prothrombin (Homo sapiens (Human))	BDBM50192107 (CHEMBL211921 | pyridine-3-carboxylic acid guanidin...) Show SMILES [#6]C1([#6])[#8]-[#5](-[#8]C1([#6])[#6])-c1ccc(cc1)-[#6](-[#8]-[#6](=O)-c1cccnc1)\[#7]=[#6](\[#7])-[#7] Show InChI InChI=1S/C20H25BN4O4/c1-19(2)20(3,4)29-21(28-19)15-9-7-13(8-10-15)16(25-18(22)23)27-17(26)14-6-5-11-24-12-14/h5-12,16H,1-4H3,(H4,22,23,25)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.23E+4	n/a	n/a	n/a	n/a	n/a	n/a
Daiichi Asubio Medical Research Laboratories, LLC Curated by ChEMBL					Assay Description Inhibition of thrombin				Bioorg Med Chem Lett 16: 5022-7 (2006) Article DOI: 10.1016/j.bmcl.2006.07.043 BindingDB Entry DOI: 10.7270/Q2PV6M5D
					More data for this Ligand-Target Pair