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SMILES: FC(F)(F)Oc1ccc(CNC(=O)N2CCC[C@H]2CN2CCCC2)cc1

InChI Key: InChIKey=XFTRPWJCEDWDHK-HNNXBMFYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50193174   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Histamine H3 receptor


(Homo sapiens (Human))		BDBM50193174
PNG
((S)-N-(4-(trifluoromethoxy)benzyl)-2-(pyrrolidin-1...)
Show SMILES FC(F)(F)Oc1ccc(CNC(=O)N2CCC[C@H]2CN2CCCC2)cc1
Show InChI InChI=1S/C18H24F3N3O2/c19-18(20,21)26-16-7-5-14(6-8-16)12-22-17(25)24-11-3-4-15(24)13-23-9-1-2-10-23/h5-8,15H,1-4,9-13H2,(H,22,25)/t15-/m0/s1
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 121n/an/an/an/an/an/an/an/a



Novo Nordisk A/S

Curated by ChEMBL


Assay Description
Binding affinity at histamine H3 receptor by hH3-[35S]GTPgamma[S] binding assay

Bioorg Med Chem Lett 16: 5303-8 (2006)


Article DOI: 10.1016/j.bmcl.2006.07.093
BindingDB Entry DOI: 10.7270/Q2RV0NBD
More data for this
Ligand-Target Pair