BDBM50193620 (E)-N-(4-amino-2-cyclobutylquinolin-6-yl)-3-(4-(trifluoromethyl)phenyl)acrylamide::CHEMBL384547

SMILES: Nc1cc(nc2ccc(NC(=O)\C=C\c3ccc(cc3)C(F)(F)F)cc12)C1CCC1

InChI Key: InChIKey=DZBRSGDTRPYNOH-IZZDOVSWSA-N

Data: 1 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50193620   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Melanin-concentrating hormone receptor (Homo sapiens (Human))	BDBM50193620 ((E)-N-(4-amino-2-cyclobutylquinolin-6-yl)-3-(4-(tr...) Show SMILES Nc1cc(nc2ccc(NC(=O)\C=C\c3ccc(cc3)C(F)(F)F)cc12)C1CCC1 Show InChI InChI=1S/C23H20F3N3O/c24-23(25,26)16-7-4-14(5-8-16)6-11-22(30)28-17-9-10-20-18(12-17)19(27)13-21(29-20)15-2-1-3-15/h4-13,15H,1-3H2,(H2,27,29)(H,28,30)/b11-6+	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of 125I-[Phe13,Tyr19]-MCH from human MCH-R1				Bioorg Med Chem Lett 16: 5275-9 (2006) Article DOI: 10.1016/j.bmcl.2006.08.008 BindingDB Entry DOI: 10.7270/Q26T0M8S
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor (Homo sapiens (Human))	BDBM50193620 ((E)-N-(4-amino-2-cyclobutylquinolin-6-yl)-3-(4-(tr...) Show SMILES Nc1cc(nc2ccc(NC(=O)\C=C\c3ccc(cc3)C(F)(F)F)cc12)C1CCC1 Show InChI InChI=1S/C23H20F3N3O/c24-23(25,26)16-7-4-14(5-8-16)6-11-22(30)28-17-9-10-20-18(12-17)19(27)13-21(29-20)15-2-1-3-15/h4-13,15H,1-3H2,(H2,27,29)(H,28,30)/b11-6+	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	250	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Stimulation of IP3-coupled mobilization of calcium in HEK293 cells expressing MCH-R1				Bioorg Med Chem Lett 16: 5275-9 (2006) Article DOI: 10.1016/j.bmcl.2006.08.008 BindingDB Entry DOI: 10.7270/Q26T0M8S
					More data for this Ligand-Target Pair