BDBM50193987 4-(3H-imidazo[4,5-c]pyridin-3-yl)-N-((R)-1-phenylethyl)pyrimidin-2-amine::CHEMBL375076

SMILES: C[C@@H](Nc1nccc(n1)-n1cnc2ccncc12)c1ccccc1

InChI Key: InChIKey=ONPQTJONKMRPSA-CYBMUJFWSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50193987   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase JAK2 (Homo sapiens (Human))	BDBM50193987 (4-(3H-imidazo[4,5-c]pyridin-3-yl)-N-((R)-1-phenyle...) Show SMILES C[C@@H](Nc1nccc(n1)-n1cnc2ccncc12)c1ccccc1 Show InChI InChI=1S/C18H16N6/c1-13(14-5-3-2-4-6-14)22-18-20-10-8-17(23-18)24-12-21-15-7-9-19-11-16(15)24/h2-13H,1H3,(H,20,22,23)/t13-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	49	n/a	n/a	n/a	n/a	n/a	n/a
Procter and Gamble Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of JAK2				Bioorg Med Chem Lett 16: 5633-8 (2006) Article DOI: 10.1016/j.bmcl.2006.08.022 BindingDB Entry DOI: 10.7270/Q2J1040K
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK3 (Homo sapiens (Human))	BDBM50193987 (4-(3H-imidazo[4,5-c]pyridin-3-yl)-N-((R)-1-phenyle...) Show SMILES C[C@@H](Nc1nccc(n1)-n1cnc2ccncc12)c1ccccc1 Show InChI InChI=1S/C18H16N6/c1-13(14-5-3-2-4-6-14)22-18-20-10-8-17(23-18)24-12-21-15-7-9-19-11-16(15)24/h2-13H,1H3,(H,20,22,23)/t13-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	145	n/a	n/a	n/a	n/a	n/a	n/a
Procter and Gamble Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of JAK3				Bioorg Med Chem Lett 16: 5633-8 (2006) Article DOI: 10.1016/j.bmcl.2006.08.022 BindingDB Entry DOI: 10.7270/Q2J1040K
					More data for this Ligand-Target Pair