Found 4 hits for monomerid = 50195042 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Acetyl-CoA carboxylase 2 (ACC2)
(Homo sapiens (Human)) | BDBM50195042
(CHEMBL220230 | N-(4-(2-(3-isobutoxyphenoxy)thiazol...)Show InChI InChI=1S/C19H22N2O3S/c1-13(2)12-23-16-6-5-7-17(10-16)24-19-20-11-18(25-19)9-8-14(3)21-15(4)22/h5-7,10-11,13-14H,12H2,1-4H3,(H,21,22) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 13 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Inhibition of human recombinant ACC2 |
Bioorg Med Chem Lett 16: 6078-81 (2006)
Article DOI: 10.1016/j.bmcl.2006.08.100 BindingDB Entry DOI: 10.7270/Q2RJ4J4W |
More data for this Ligand-Target Pair | |
Acetyl-CoA carboxylase 1 (ACC1)
(Homo sapiens (Human)) | BDBM50195042
(CHEMBL220230 | N-(4-(2-(3-isobutoxyphenoxy)thiazol...)Show InChI InChI=1S/C19H22N2O3S/c1-13(2)12-23-16-6-5-7-17(10-16)24-19-20-11-18(25-19)9-8-14(3)21-15(4)22/h5-7,10-11,13-14H,12H2,1-4H3,(H,21,22) | PDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 72 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Inhibition of human recombinant ACC1 |
Bioorg Med Chem Lett 17: 1961-5 (2007)
Article DOI: 10.1016/j.bmcl.2007.01.022 BindingDB Entry DOI: 10.7270/Q2W095KS |
More data for this Ligand-Target Pair | |
Acetyl-CoA carboxylase 1 (ACC1)
(Homo sapiens (Human)) | BDBM50195042
(CHEMBL220230 | N-(4-(2-(3-isobutoxyphenoxy)thiazol...)Show InChI InChI=1S/C19H22N2O3S/c1-13(2)12-23-16-6-5-7-17(10-16)24-19-20-11-18(25-19)9-8-14(3)21-15(4)22/h5-7,10-11,13-14H,12H2,1-4H3,(H,21,22) | PDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 72 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Inhibition of human recombinant ACC1 |
Bioorg Med Chem Lett 16: 6078-81 (2006)
Article DOI: 10.1016/j.bmcl.2006.08.100 BindingDB Entry DOI: 10.7270/Q2RJ4J4W |
More data for this Ligand-Target Pair | |
Acetyl-CoA carboxylase 2 (ACC2)
(Homo sapiens (Human)) | BDBM50195042
(CHEMBL220230 | N-(4-(2-(3-isobutoxyphenoxy)thiazol...)Show InChI InChI=1S/C19H22N2O3S/c1-13(2)12-23-16-6-5-7-17(10-16)24-19-20-11-18(25-19)9-8-14(3)21-15(4)22/h5-7,10-11,13-14H,12H2,1-4H3,(H,21,22) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 13 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Inhibition of human recombinant ACC2 |
Bioorg Med Chem Lett 17: 1961-5 (2007)
Article DOI: 10.1016/j.bmcl.2007.01.022 BindingDB Entry DOI: 10.7270/Q2W095KS |
More data for this Ligand-Target Pair | |