null

SMILES: Clc1cc(Oc2ccccn2)cc(c1)N1Cc2ccccc2S1(=O)=O

InChI Key: InChIKey=ROJVYIHWPWITEK-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50196402   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Free fatty acid receptor 4 (Homo sapiens (Human))	BDBM50196402 (CHEMBL3910333) Show SMILES Clc1cc(Oc2ccccn2)cc(c1)N1Cc2ccccc2S1(=O)=O Show InChI InChI=1S/C18H13ClN2O3S/c19-14-9-15(11-16(10-14)24-18-7-3-4-8-20-18)21-12-13-5-1-2-6-17(13)25(21,22)23/h1-11H,12H2	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	138	n/a	n/a	n/a	n/a
University of Southern Denmark Curated by ChEMBL					Assay Description Agonist activity at C-terminal YFP-tagged human FFA4 expressed in HEK293 cells in presence of coelentrazine h by BRET based beta-arrestin-2 interacti...				J Med Chem 59: 8868-8878 (2016) Article DOI: 10.1021/acs.jmedchem.6b00685 BindingDB Entry DOI: 10.7270/Q2C53NS2
					More data for this Ligand-Target Pair
Free fatty acid receptor 4 (Homo sapiens (Human))	BDBM50196402 (CHEMBL3910333) Show SMILES Clc1cc(Oc2ccccn2)cc(c1)N1Cc2ccccc2S1(=O)=O Show InChI InChI=1S/C18H13ClN2O3S/c19-14-9-15(11-16(10-14)24-18-7-3-4-8-20-18)21-12-13-5-1-2-6-17(13)25(21,22)23/h1-11H,12H2	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	39	n/a	n/a	n/a	n/a
University of Southern Denmark Curated by ChEMBL					Assay Description Agonist activity at human FFA4 expressed in human Flp-In T-REx293 cells by Fura2-AM dye based calcium mobilization assay				J Med Chem 59: 8868-8878 (2016) Article DOI: 10.1021/acs.jmedchem.6b00685 BindingDB Entry DOI: 10.7270/Q2C53NS2
					More data for this Ligand-Target Pair
Free fatty acid receptor 1 (Homo sapiens (Human))	BDBM50196402 (CHEMBL3910333) Show SMILES Clc1cc(Oc2ccccn2)cc(c1)N1Cc2ccccc2S1(=O)=O Show InChI InChI=1S/C18H13ClN2O3S/c19-14-9-15(11-16(10-14)24-18-7-3-4-8-20-18)21-12-13-5-1-2-6-17(13)25(21,22)23/h1-11H,12H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	<1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Southern Denmark Curated by ChEMBL					Assay Description Antagonist activity against human FFA1 expressed in human Flp-In T-REx293 cells assessed as as reduction in TUG770-induced response by Fura2-AM dye b...				J Med Chem 59: 8868-8878 (2016) Article DOI: 10.1021/acs.jmedchem.6b00685 BindingDB Entry DOI: 10.7270/Q2C53NS2
					More data for this Ligand-Target Pair
Free fatty acid receptor 4 (Homo sapiens (Human))	BDBM50196402 (CHEMBL3910333) Show SMILES Clc1cc(Oc2ccccn2)cc(c1)N1Cc2ccccc2S1(=O)=O Show InChI InChI=1S/C18H13ClN2O3S/c19-14-9-15(11-16(10-14)24-18-7-3-4-8-20-18)21-12-13-5-1-2-6-17(13)25(21,22)23/h1-11H,12H2	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	40	n/a	n/a	n/a	n/a
University of Southern Denmark Curated by ChEMBL					Assay Description Agonist activity at C-terminal YFP-tagged human FFA4 expressed in HEK293 cells in presence of coelentrazine h by BRET based beta-arrestin-2 interacti...				J Med Chem 59: 8868-8878 (2016) Article DOI: 10.1021/acs.jmedchem.6b00685 BindingDB Entry DOI: 10.7270/Q2C53NS2
					More data for this Ligand-Target Pair
Free fatty acid receptor 4 (Mus musculus)	BDBM50196402 (CHEMBL3910333) Show SMILES Clc1cc(Oc2ccccn2)cc(c1)N1Cc2ccccc2S1(=O)=O Show InChI InChI=1S/C18H13ClN2O3S/c19-14-9-15(11-16(10-14)24-18-7-3-4-8-20-18)21-12-13-5-1-2-6-17(13)25(21,22)23/h1-11H,12H2	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	72	n/a	n/a	n/a	n/a
University of Southern Denmark Curated by ChEMBL					Assay Description Agonist activity mouse FFA4 by Gq-dependent calcium mobilization assay				J Med Chem 59: 8868-8878 (2016) Article DOI: 10.1021/acs.jmedchem.6b00685 BindingDB Entry DOI: 10.7270/Q2C53NS2
					More data for this Ligand-Target Pair