BDBM50196663 12-(3-adamantan-1-yl-ureido)-dodecanoic acid naphthalen-1-ylmethyl ester::CHEMBL224579

SMILES: O=C(CCCCCCCCCCCNC(=O)NC12CC3CC(CC(C3)C1)C2)OCc1cccc2ccccc12

InChI Key: InChIKey=JGZXXZODNQCHGR-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50196663   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Soluble epoxide hydrolase (sEH) (Mus musculus (Mouse))	BDBM50196663 (12-(3-adamantan-1-yl-ureido)-dodecanoic acid napht...) Show SMILES O=C(CCCCCCCCCCCNC(=O)NC12CC3CC(CC(C3)C1)C2)OCc1cccc2ccccc12 |TLB:16:17:20:24.23.22,THB:18:19:22:26.17.25,18:17:20.19.24:22,25:17:20:24.23.22,25:23:20:26.18.17| Show InChI InChI=1S/C34H48N2O3/c37-32(39-25-30-15-12-14-29-13-9-10-16-31(29)30)17-8-6-4-2-1-3-5-7-11-18-35-33(38)36-34-22-26-19-27(23-34)21-28(20-26)24-34/h9-10,12-16,26-28H,1-8,11,17-25H2,(H2,35,36,38)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	90	n/a	n/a	n/a	n/a	n/a	n/a
Department of Entomology and University of California Davis Cancer Center Curated by ChEMBL					Assay Description Inhibition of mouse soluble epoxide hydrolase by spectrometric based assay				Bioorg Med Chem 15: 312-23 (2006) Article DOI: 10.1016/j.bmc.2006.09.057 BindingDB Entry DOI: 10.7270/Q26D5SNJ
					More data for this Ligand-Target Pair
EBifunctional epoxide hydrolase 2 (Homo sapiens (Human))	BDBM50196663 (12-(3-adamantan-1-yl-ureido)-dodecanoic acid napht...) Show SMILES O=C(CCCCCCCCCCCNC(=O)NC12CC3CC(CC(C3)C1)C2)OCc1cccc2ccccc12 |TLB:16:17:20:24.23.22,THB:18:19:22:26.17.25,18:17:20.19.24:22,25:17:20:24.23.22,25:23:20:26.18.17| Show InChI InChI=1S/C34H48N2O3/c37-32(39-25-30-15-12-14-29-13-9-10-16-31(29)30)17-8-6-4-2-1-3-5-7-11-18-35-33(38)36-34-22-26-19-27(23-34)21-28(20-26)24-34/h9-10,12-16,26-28H,1-8,11,17-25H2,(H2,35,36,38)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.40	n/a	n/a	n/a	n/a	n/a	n/a
Department of Entomology and University of California Davis Cancer Center Curated by ChEMBL					Assay Description Inhibition of human soluble epoxide hydrolase by fluorescent based assay				Bioorg Med Chem 15: 312-23 (2006) Article DOI: 10.1016/j.bmc.2006.09.057 BindingDB Entry DOI: 10.7270/Q26D5SNJ
					More data for this Ligand-Target Pair
EBifunctional epoxide hydrolase 2 (Homo sapiens (Human))	BDBM50196663 (12-(3-adamantan-1-yl-ureido)-dodecanoic acid napht...) Show SMILES O=C(CCCCCCCCCCCNC(=O)NC12CC3CC(CC(C3)C1)C2)OCc1cccc2ccccc12 |TLB:16:17:20:24.23.22,THB:18:19:22:26.17.25,18:17:20.19.24:22,25:17:20:24.23.22,25:23:20:26.18.17| Show InChI InChI=1S/C34H48N2O3/c37-32(39-25-30-15-12-14-29-13-9-10-16-31(29)30)17-8-6-4-2-1-3-5-7-11-18-35-33(38)36-34-22-26-19-27(23-34)21-28(20-26)24-34/h9-10,12-16,26-28H,1-8,11,17-25H2,(H2,35,36,38)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	210	n/a	n/a	n/a	n/a	n/a	n/a
Department of Entomology and University of California Davis Cancer Center Curated by ChEMBL					Assay Description Inhibition of human soluble epoxide hydrolase by spectrometric based assay				Bioorg Med Chem 15: 312-23 (2006) Article DOI: 10.1016/j.bmc.2006.09.057 BindingDB Entry DOI: 10.7270/Q26D5SNJ
					More data for this Ligand-Target Pair