BDBM50196927 CHEMBL3938810

SMILES: Cc1ccccc1S(=O)(=O)NC([C@H](N)C(O)=O)C(O)=O

InChI Key: InChIKey=COGJSNZLBJCRKR-IENPIDJESA-N

Data: 6 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50196927   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Excitatory amino acid transporter 2 (Homo sapiens (Human))	BDBM50196927 (CHEMBL3938810) Show SMILES Cc1ccccc1S(=O)(=O)NC([C@H](N)C(O)=O)C(O)=O |r| Show InChI InChI=1S/C11H14N2O6S/c1-6-4-2-3-5-7(6)20(18,19)13-9(11(16)17)8(12)10(14)15/h2-5,8-9,13H,12H2,1H3,(H,14,15)(H,16,17)/t8-,9?/m0/s1	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	6.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Inhibition of [3H]-D-Asp uptake at human EAAT2 expressed in HEK293 cells measured after 3 mins by TopCount method				J Med Chem 59: 8771-8786 (2016) Article DOI: 10.1021/acs.jmedchem.6b01066 BindingDB Entry DOI: 10.7270/Q2Z03B4C
					More data for this Ligand-Target Pair
Excitatory amino acid transporter 2 (Homo sapiens (Human))	BDBM50196927 (CHEMBL3938810) Show SMILES Cc1ccccc1S(=O)(=O)NC([C@H](N)C(O)=O)C(O)=O |r| Show InChI InChI=1S/C11H14N2O6S/c1-6-4-2-3-5-7(6)20(18,19)13-9(11(16)17)8(12)10(14)15/h2-5,8-9,13H,12H2,1H3,(H,14,15)(H,16,17)/t8-,9?/m0/s1	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	6.61E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Inhibition of [3H]-D-Asp uptake at human EAAT2 expressed in HEK293 cells measured after 3 mins by TopCount method				J Med Chem 59: 8771-8786 (2016) Article DOI: 10.1021/acs.jmedchem.6b01066 BindingDB Entry DOI: 10.7270/Q2Z03B4C
					More data for this Ligand-Target Pair
Excitatory amino acid transporter 1 (Homo sapiens (Human))	BDBM50196927 (CHEMBL3938810) Show SMILES Cc1ccccc1S(=O)(=O)NC([C@H](N)C(O)=O)C(O)=O |r| Show InChI InChI=1S/C11H14N2O6S/c1-6-4-2-3-5-7(6)20(18,19)13-9(11(16)17)8(12)10(14)15/h2-5,8-9,13H,12H2,1H3,(H,14,15)(H,16,17)/t8-,9?/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.75E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Inhibition of [3H]-D-Asp uptake at human EAAT1 expressed in HEK293 cells measured after 3 mins by TopCount method				J Med Chem 59: 8771-8786 (2016) Article DOI: 10.1021/acs.jmedchem.6b01066 BindingDB Entry DOI: 10.7270/Q2Z03B4C
					More data for this Ligand-Target Pair
Excitatory amino acid transporter 3 (Homo sapiens (Human))	BDBM50196927 (CHEMBL3938810) Show SMILES Cc1ccccc1S(=O)(=O)NC([C@H](N)C(O)=O)C(O)=O |r| Show InChI InChI=1S/C11H14N2O6S/c1-6-4-2-3-5-7(6)20(18,19)13-9(11(16)17)8(12)10(14)15/h2-5,8-9,13H,12H2,1H3,(H,14,15)(H,16,17)/t8-,9?/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	8.71E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Inhibition of [3H]-D-Asp uptake at human EAAT3 expressed in HEK293 cells measured after 3 mins by TopCount method				J Med Chem 59: 8771-8786 (2016) Article DOI: 10.1021/acs.jmedchem.6b01066 BindingDB Entry DOI: 10.7270/Q2Z03B4C
					More data for this Ligand-Target Pair
Excitatory amino acid transporter 3 (Homo sapiens (Human))	BDBM50196927 (CHEMBL3938810) Show SMILES Cc1ccccc1S(=O)(=O)NC([C@H](N)C(O)=O)C(O)=O |r| Show InChI InChI=1S/C11H14N2O6S/c1-6-4-2-3-5-7(6)20(18,19)13-9(11(16)17)8(12)10(14)15/h2-5,8-9,13H,12H2,1H3,(H,14,15)(H,16,17)/t8-,9?/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	8.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Inhibition of [3H]-D-Asp uptake at human EAAT3 expressed in HEK293 cells measured after 3 mins by TopCount method				J Med Chem 59: 8771-8786 (2016) Article DOI: 10.1021/acs.jmedchem.6b01066 BindingDB Entry DOI: 10.7270/Q2Z03B4C
					More data for this Ligand-Target Pair
Excitatory amino acid transporter 1 (Homo sapiens (Human))	BDBM50196927 (CHEMBL3938810) Show SMILES Cc1ccccc1S(=O)(=O)NC([C@H](N)C(O)=O)C(O)=O |r| Show InChI InChI=1S/C11H14N2O6S/c1-6-4-2-3-5-7(6)20(18,19)13-9(11(16)17)8(12)10(14)15/h2-5,8-9,13H,12H2,1H3,(H,14,15)(H,16,17)/t8-,9?/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Inhibition of [3H]-D-Asp uptake at human EAAT1 expressed in HEK293 cells measured after 3 mins by TopCount method				J Med Chem 59: 8771-8786 (2016) Article DOI: 10.1021/acs.jmedchem.6b01066 BindingDB Entry DOI: 10.7270/Q2Z03B4C
					More data for this Ligand-Target Pair