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SMILES: COc1ccc2c3C[C@H](N)[C@H](Oc3ccc2c1)c1cc(F)c(F)cc1F

InChI Key: InChIKey=KGBMSMHIQJKLGU-AZUAARDMSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50198178   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dipeptidyl peptidase 4 (Homo sapiens (Human))	BDBM50198178 (CHEMBL3901191 | US10479798, Compound 6) Show SMILES COc1ccc2c3C[C@H](N)[C@H](Oc3ccc2c1)c1cc(F)c(F)cc1F |r| Show InChI InChI=1S/C20H16F3NO2/c1-25-11-3-4-12-10(6-11)2-5-19-13(12)8-18(24)20(26-19)14-7-16(22)17(23)9-15(14)21/h2-7,9,18,20H,8,24H2,1H3/t18-,20+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	US Patent	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY; SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES US Patent					Assay Description Screening Method:Name of method: Activity Evaluation of DPP4, Fluorescence.Instrument: Microplate reader, Envision (PerkinElmer, USA).Material: human...				US Patent US10479798 (2019) BindingDB Entry DOI: 10.7270/Q2377C4Z
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 4 (Homo sapiens (Human))	BDBM50198178 (CHEMBL3901191 | US10479798, Compound 6) Show SMILES COc1ccc2c3C[C@H](N)[C@H](Oc3ccc2c1)c1cc(F)c(F)cc1F |r| Show InChI InChI=1S/C20H16F3NO2/c1-25-11-3-4-12-10(6-11)2-5-19-13(12)8-18(24)20(26-19)14-7-16(22)17(23)9-15(14)21/h2-7,9,18,20H,8,24H2,1H3/t18-,20+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
East China University of Science and Technology Curated by ChEMBL					Assay Description Inhibition of DPP4 (unknown origin) expressed in Sf9 cells using Gly-Pro-AMC substrate				J Med Chem 59: 6772-90 (2016) Article DOI: 10.1021/acs.jmedchem.6b00505 BindingDB Entry DOI: 10.7270/Q2DV1MWF
					More data for this Ligand-Target Pair