BDBM50198190 CHEMBL3920234

SMILES: N[C@@H]1Cc2c(O[C@H]1c1cc(F)c(F)cc1F)ccc1cc(ccc21)C#N

InChI Key: InChIKey=IHMRKDWNSLQDOV-QUCCMNQESA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50198190   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dipeptidyl peptidase 4 (Homo sapiens (Human))	BDBM50198190 (CHEMBL3920234) Show SMILES N[C@@H]1Cc2c(O[C@H]1c1cc(F)c(F)cc1F)ccc1cc(ccc21)C#N |r| Show InChI InChI=1S/C20H13F3N2O/c21-15-8-17(23)16(22)6-14(15)20-18(25)7-13-12-3-1-10(9-24)5-11(12)2-4-19(13)26-20/h1-6,8,18,20H,7,25H2/t18-,20+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.40	n/a	n/a	n/a	n/a	n/a	n/a
East China University of Science and Technology Curated by ChEMBL					Assay Description Inhibition of DPP4 (unknown origin) expressed in Sf9 cells using Gly-Pro-AMC substrate				J Med Chem 59: 6772-90 (2016) Article DOI: 10.1021/acs.jmedchem.6b00505 BindingDB Entry DOI: 10.7270/Q2DV1MWF
					More data for this Ligand-Target Pair