BDBM50198282 1-((1H-indol-3-yl)methyl)-4-(4-fluorophenyl)piperidin-4-ol::CHEMBL246849
SMILES: OC1(CCN(Cc2c[nH]c3ccccc23)CC1)c1ccc(F)cc1
InChI Key: InChIKey=QCXHSUNSZGYUFF-UHFFFAOYSA-N
Data: 3 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
D(2) dopamine receptor (Homo sapiens (Human)) | BDBM50198282 (1-((1H-indol-3-yl)methyl)-4-(4-fluorophenyl)piperi...) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 127 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute on Drug Abuse-Intramural Research Program Curated by ChEMBL | Assay Description Displacement of [125I]IABN from human dopamine D2L receptor expressed in HEK293 cells | Bioorg Med Chem Lett 17: 745-9 (2007) Article DOI: 10.1016/j.bmcl.2006.10.076 BindingDB Entry DOI: 10.7270/Q2N879FG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(3) dopamine receptor (Homo sapiens (Human)) | BDBM50198282 (1-((1H-indol-3-yl)methyl)-4-(4-fluorophenyl)piperi...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 490 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute on Drug Abuse-Intramural Research Program Curated by ChEMBL | Assay Description Displacement of [125I]IABN from human dopamine D3 receptor expressed in HEK293 cells | Bioorg Med Chem Lett 17: 745-9 (2007) Article DOI: 10.1016/j.bmcl.2006.10.076 BindingDB Entry DOI: 10.7270/Q2N879FG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(4) dopamine receptor (Homo sapiens (Human)) | BDBM50198282 (1-((1H-indol-3-yl)methyl)-4-(4-fluorophenyl)piperi...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 6.09E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute on Drug Abuse-Intramural Research Program Curated by ChEMBL | Assay Description Displacement of [125I]IABN from human dopamine D4 receptor expressed in HEK293 cells | Bioorg Med Chem Lett 17: 745-9 (2007) Article DOI: 10.1016/j.bmcl.2006.10.076 BindingDB Entry DOI: 10.7270/Q2N879FG | |||||||||||
More data for this Ligand-Target Pair |