BDBM50198418 1-(1-(cyclooctenylmethyl)piperidin-4-yl)-3-(3,5-dichlorophenyl)urea::CHEMBL243341

SMILES: Clc1cc(Cl)cc(NC(=O)NC2CCN(C\C3=C\CCCCCC3)CC2)c1

InChI Key: InChIKey=MWEGETXRJZIQJZ-OMCISZLKSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50198418   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
chemokine (C-X-C motif) receptor 3 (Homo sapiens (Human))	BDBM50198418 (1-(1-(cyclooctenylmethyl)piperidin-4-yl)-3-(3,5-di...) Show SMILES Clc1cc(Cl)cc(NC(=O)NC2CCN(C\C3=C\CCCCCC3)CC2)c1 |t:16| Show InChI InChI=1S/C21H29Cl2N3O/c22-17-12-18(23)14-20(13-17)25-21(27)24-19-8-10-26(11-9-19)15-16-6-4-2-1-3-5-7-16/h6,12-14,19H,1-5,7-11,15H2,(H2,24,25,27)/b16-6+	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	41	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
UCB Curated by ChEMBL					Assay Description Antagonist activity at human CXCR3 expressed in CHO cells by [35S]GTPgammaS binding assay				Bioorg Med Chem Lett 17: 697-701 (2007) Article DOI: 10.1016/j.bmcl.2006.10.088 BindingDB Entry DOI: 10.7270/Q2833RPB
					More data for this Ligand-Target Pair