BDBM50198672 CHEMBL3939561

SMILES: COc1cc2oc(=O)cc(C)c2cc1-c1ccc(C#N)n1Cc1ccc(F)cc1

InChI Key: InChIKey=DYZJWTFYVLRGLB-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50198672   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Progesterone receptor (Homo sapiens (Human))	BDBM50198672 (CHEMBL3939561) Show SMILES COc1cc2oc(=O)cc(C)c2cc1-c1ccc(C#N)n1Cc1ccc(F)cc1 Show InChI InChI=1S/C23H17FN2O3/c1-14-9-23(27)29-22-11-21(28-2)19(10-18(14)22)20-8-7-17(12-25)26(20)13-15-3-5-16(24)6-4-15/h3-11H,13H2,1-2H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	570	n/a	n/a	n/a	n/a	n/a	n/a
Ochanomizu University Curated by ChEMBL					Assay Description Antagonist activity at PR in human T47D cells assessed as inhibition of progesterone-induced alkaline phosphatase expression after 24 hrs by alkaline...				Bioorg Med Chem 24: 5602-5610 (2016) Article DOI: 10.1016/j.bmc.2016.09.020 BindingDB Entry DOI: 10.7270/Q2R49SRM
					More data for this Ligand-Target Pair