BDBM50198673 CHEMBL3975572

SMILES: Cc1cc(=O)oc2cc(O)c(cc12)-c1ccc(C#N)n1C

InChI Key: InChIKey=SBSAZAWOVDYWIT-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50198673   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Progesterone receptor (Homo sapiens (Human))	BDBM50198673 (CHEMBL3975572) Show SMILES Cc1cc(=O)oc2cc(O)c(cc12)-c1ccc(C#N)n1C Show InChI InChI=1S/C16H12N2O3/c1-9-5-16(20)21-15-7-14(19)12(6-11(9)15)13-4-3-10(8-17)18(13)2/h3-7,19H,1-2H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
Ochanomizu University Curated by ChEMBL					Assay Description Antagonist activity at PR in human T47D cells assessed as inhibition of progesterone-induced alkaline phosphatase expression after 24 hrs by alkaline...				Bioorg Med Chem 24: 5602-5610 (2016) Article DOI: 10.1016/j.bmc.2016.09.020 BindingDB Entry DOI: 10.7270/Q2R49SRM
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50198673 (CHEMBL3975572) Show SMILES Cc1cc(=O)oc2cc(O)c(cc12)-c1ccc(C#N)n1C Show InChI InChI=1S/C16H12N2O3/c1-9-5-16(20)21-15-7-14(19)12(6-11(9)15)13-4-3-10(8-17)18(13)2/h3-7,19H,1-2H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.57E+4	n/a	n/a	n/a	n/a	n/a	n/a
Ochanomizu University Curated by ChEMBL					Assay Description Displacement of [1,2,6,7-3H]progesterone from recombinant human GST-tagged PR-LBD (675 to 933 residues) expressed in baculovirus-infected insect cell...				Bioorg Med Chem 24: 5602-5610 (2016) Article DOI: 10.1016/j.bmc.2016.09.020 BindingDB Entry DOI: 10.7270/Q2R49SRM
					More data for this Ligand-Target Pair