BDBM50198719 CHEMBL3962373

SMILES: FC(F)(F)c1ccc(c(Cl)c1)-n1nc(C(=O)NC2(CC2)c2ccccn2)c2CCC\C(=C/c3ccc(Cl)s3)c12

InChI Key: InChIKey=JRHNCIILHNCYSB-JQIJEIRASA-N

Data: 2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50198719   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50198719 (CHEMBL3962373) Show SMILES FC(F)(F)c1ccc(c(Cl)c1)-n1nc(C(=O)NC2(CC2)c2ccccn2)c2CCC\C(=C/c3ccc(Cl)s3)c12 Show InChI InChI=1S/C28H21Cl2F3N4OS/c29-20-15-17(28(31,32)33)7-9-21(20)37-25-16(14-18-8-10-23(30)39-18)4-3-5-19(25)24(36-37)26(38)35-27(11-12-27)22-6-1-2-13-34-22/h1-2,6-10,13-15H,3-5,11-12H2,(H,35,38)/b16-14+	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	11	n/a	n/a	n/a	n/a
Janssen Research& Development, L.L.C. Curated by ChEMBL					Assay Description Inverse agonist activity at human cannabinoid receptor 1 expressed in HEK293 cells assessed as increase in forskolin-induced cAMP production preincub...				Bioorg Med Chem Lett 26: 5346-5349 (2016) Article DOI: 10.1016/j.bmcl.2016.09.025 BindingDB Entry DOI: 10.7270/Q2MC9207
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM50198719 (CHEMBL3962373) Show SMILES FC(F)(F)c1ccc(c(Cl)c1)-n1nc(C(=O)NC2(CC2)c2ccccn2)c2CCC\C(=C/c3ccc(Cl)s3)c12 Show InChI InChI=1S/C28H21Cl2F3N4OS/c29-20-15-17(28(31,32)33)7-9-21(20)37-25-16(14-18-8-10-23(30)39-18)4-3-5-19(25)24(36-37)26(38)35-27(11-12-27)22-6-1-2-13-34-22/h1-2,6-10,13-15H,3-5,11-12H2,(H,35,38)/b16-14+	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Janssen Research& Development, L.L.C. Curated by ChEMBL					Assay Description Inverse agonist activity at human cannabinoid receptor 2 expressed in HEK293 cells assessed as increase in forskolin-induced cAMP production preincub...				Bioorg Med Chem Lett 26: 5346-5349 (2016) Article DOI: 10.1016/j.bmcl.2016.09.025 BindingDB Entry DOI: 10.7270/Q2MC9207
					More data for this Ligand-Target Pair