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SMILES: CN(C)Cc1cc2cc(ccc2s1)-n1cnc2cc(sc2c1=O)-c1ccc(Cl)cc1

InChI Key: InChIKey=XJMIODNDCXPYKT-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50199260   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Melanin-concentrating hormone receptor 1


(Homo sapiens (Human))		BDBM50199260
PNG
(6-(4-chlorophenyl)-3-{2-[(dimethylamino)methyl]-1-...)
Show SMILES CN(C)Cc1cc2cc(ccc2s1)-n1cnc2cc(sc2c1=O)-c1ccc(Cl)cc1
Show InChI InChI=1S/C23H18ClN3OS2/c1-26(2)12-18-10-15-9-17(7-8-20(15)29-18)27-13-25-19-11-21(30-22(19)23(27)28)14-3-5-16(24)6-4-14/h3-11,13H,12H2,1-2H3
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n/an/a 1.30n/an/an/an/an/an/a



GlaxoSmithKline

Curated by ChEMBL


Assay Description
Antagonist activity against human MCH1 receptor stably-expressed in CHO cells by Gal4/Elk1-Luc reporter assay

J Med Chem 49: 7108-18 (2006)


Article DOI: 10.1021/jm060814b
BindingDB Entry DOI: 10.7270/Q2JD4WFT
More data for this
Ligand-Target Pair