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SMILES: Nc1nccn2c(nc(-c3cccc(OCc4ccccc4OC(F)F)c3)c12)C1CCC1

InChI Key: InChIKey=SYXCOPRMXTYKNO-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50199653   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Insulin-like growth factor 1 receptor


(Homo sapiens (Human))		BDBM50199653
PNG
(1-(3-(2-(difluoromethoxy)benzyloxy)phenyl)-3-cyclo...)
Show SMILES Nc1nccn2c(nc(-c3cccc(OCc4ccccc4OC(F)F)c3)c12)C1CCC1
Show InChI InChI=1S/C24H22F2N4O2/c25-24(26)32-19-10-2-1-5-17(19)14-31-18-9-4-8-16(13-18)20-21-22(27)28-11-12-30(21)23(29-20)15-6-3-7-15/h1-2,4-5,8-13,15,24H,3,6-7,14H2,(H2,27,28)
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Article
PubMed
n/an/a 3.28E+3n/an/an/an/an/an/a



OSI Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Inhibition of human recombinant GST-IGF1R activity

Bioorg Med Chem Lett 17: 1091-7 (2007)


Article DOI: 10.1016/j.bmcl.2006.11.016
BindingDB Entry DOI: 10.7270/Q2QZ29MB
More data for this
Ligand-Target Pair