BDBM50200745 7-(4-fluorophenyl)-2-(4-(piperidin-1-ylmethyl)phenethyl)-3,4-dihydropyrrolo[1,2-a]pyrazin-1(2H)-one::CHEMBL216280
SMILES: Fc1ccc(cc1)-c1cc2C(=O)N(CCc3ccc(CN4CCCCC4)cc3)CCn2c1
InChI Key: InChIKey=QOKHHPNTBNJONY-UHFFFAOYSA-N
Data: 2 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Melanin-concentrating hormone receptor (Homo sapiens (Human)) | BDBM50200745![]() (7-(4-fluorophenyl)-2-(4-(piperidin-1-ylmethyl)phen...) | Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 23 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Procter and Gamble Pharmaceuticals Curated by ChEMBL | Assay Description Functional antagonism of MCH-R1 expressed in HEK293 cells | Bioorg Med Chem Lett 17: 657-61 (2007) Article DOI: 10.1016/j.bmcl.2006.10.096 BindingDB Entry DOI: 10.7270/Q2QR4WS9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2C (Homo sapiens (Human)) | BDBM50200745![]() (7-(4-fluorophenyl)-2-(4-(piperidin-1-ylmethyl)phen...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 100 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Procter and Gamble Pharmaceuticals Curated by ChEMBL | Assay Description Inhibition of binding to serotonin receptor 5HT2C | Bioorg Med Chem Lett 17: 657-61 (2007) Article DOI: 10.1016/j.bmcl.2006.10.096 BindingDB Entry DOI: 10.7270/Q2QR4WS9 | |||||||||||
More data for this Ligand-Target Pair |