Found 5 hits for monomerid = 50201302 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Aurora kinase B
(Homo sapiens (Human)) | BDBM50201302
(1-(4-(4-amino-7-phenylthieno[3,2-c]pyridin-3-yl)ph...)Show SMILES Cc1cccc(NC(=O)Nc2ccc(cc2)-c2csc3c(cnc(N)c23)-c2ccccc2)c1 Show InChI InChI=1S/C27H22N4OS/c1-17-6-5-9-21(14-17)31-27(32)30-20-12-10-19(11-13-20)23-16-33-25-22(15-29-26(28)24(23)25)18-7-3-2-4-8-18/h2-16H,1H3,(H2,28,29)(H2,30,31,32) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 3.28E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Inhibition of Aurora B using 1 mM ATP by HTRF assay |
Bioorg Med Chem Lett 22: 3208-12 (2012)
Article DOI: 10.1016/j.bmcl.2012.03.035 BindingDB Entry DOI: 10.7270/Q2000336 |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50201302
(1-(4-(4-amino-7-phenylthieno[3,2-c]pyridin-3-yl)ph...)Show SMILES Cc1cccc(NC(=O)Nc2ccc(cc2)-c2csc3c(cnc(N)c23)-c2ccccc2)c1 Show InChI InChI=1S/C27H22N4OS/c1-17-6-5-9-21(14-17)31-27(32)30-20-12-10-19(11-13-20)23-16-33-25-22(15-29-26(28)24(23)25)18-7-3-2-4-8-18/h2-16H,1H3,(H2,28,29)(H2,30,31,32) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 33 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Inhibition of human KDR phosphorylation expressed in mouse NIH3T3 cells |
Bioorg Med Chem Lett 22: 3208-12 (2012)
Article DOI: 10.1016/j.bmcl.2012.03.035 BindingDB Entry DOI: 10.7270/Q2000336 |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50201302
(1-(4-(4-amino-7-phenylthieno[3,2-c]pyridin-3-yl)ph...)Show SMILES Cc1cccc(NC(=O)Nc2ccc(cc2)-c2csc3c(cnc(N)c23)-c2ccccc2)c1 Show InChI InChI=1S/C27H22N4OS/c1-17-6-5-9-21(14-17)31-27(32)30-20-12-10-19(11-13-20)23-16-33-25-22(15-29-26(28)24(23)25)18-7-3-2-4-8-18/h2-16H,1H3,(H2,28,29)(H2,30,31,32) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 13 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Inhibition of human KDR phosphorylation expressed in mouse NIH3T3 cells |
Bioorg Med Chem Lett 22: 3208-12 (2012)
Article DOI: 10.1016/j.bmcl.2012.03.035 BindingDB Entry DOI: 10.7270/Q2000336 |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50201302
(1-(4-(4-amino-7-phenylthieno[3,2-c]pyridin-3-yl)ph...)Show SMILES Cc1cccc(NC(=O)Nc2ccc(cc2)-c2csc3c(cnc(N)c23)-c2ccccc2)c1 Show InChI InChI=1S/C27H22N4OS/c1-17-6-5-9-21(14-17)31-27(32)30-20-12-10-19(11-13-20)23-16-33-25-22(15-29-26(28)24(23)25)18-7-3-2-4-8-18/h2-16H,1H3,(H2,28,29)(H2,30,31,32) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 13 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Inhibition of KDR |
Bioorg Med Chem Lett 17: 1246-9 (2007)
Article DOI: 10.1016/j.bmcl.2006.12.015 BindingDB Entry DOI: 10.7270/Q28K78RS |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50201302
(1-(4-(4-amino-7-phenylthieno[3,2-c]pyridin-3-yl)ph...)Show SMILES Cc1cccc(NC(=O)Nc2ccc(cc2)-c2csc3c(cnc(N)c23)-c2ccccc2)c1 Show InChI InChI=1S/C27H22N4OS/c1-17-6-5-9-21(14-17)31-27(32)30-20-12-10-19(11-13-20)23-16-33-25-22(15-29-26(28)24(23)25)18-7-3-2-4-8-18/h2-16H,1H3,(H2,28,29)(H2,30,31,32) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 33 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Inhibition of human KDR phosphorylation in NIH3T3 cells |
Bioorg Med Chem Lett 17: 1246-9 (2007)
Article DOI: 10.1016/j.bmcl.2006.12.015 BindingDB Entry DOI: 10.7270/Q28K78RS |
More data for this Ligand-Target Pair | |